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Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques.
Lee JH, Yang DS, Goulbourne CN, Im E, Stavrides P, Pensalfini A, Chan H, Bouchet-Marquis C, Bleiwas C, Berg MJ, Huo C, Peddy J, Pawlik M, Levy E, Rao M, Staufenbiel M, Nixon RA. Lee JH, et al. Among authors: levy e. Nat Neurosci. 2022 Jun;25(6):688-701. doi: 10.1038/s41593-022-01084-8. Epub 2022 Jun 2. Nat Neurosci. 2022. PMID: 35654956 Free PMC article.
Proteins that bind to the RERMS region of beta amyloid precursor protein.
Pawlik M, Otero DA, Park M, Fischer WH, Levy E, Saitoh T. Pawlik M, et al. Among authors: levy e. Biochem Biophys Res Commun. 2007 Apr 20;355(4):907-12. doi: 10.1016/j.bbrc.2007.02.047. Epub 2007 Feb 20. Biochem Biophys Res Commun. 2007. PMID: 17335780 Free PMC article.
2,406 results