Christensen H - Search Results

1

Correlations between 4β-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range.

Eide Kvitne K, Hole K, Krogstad V, Wollmann BM, Wegler C, Johnson LK, Hertel JK, Artursson P, Karlsson C, Andersson S, Andersson TB, Sandbu R, Hjelmesæth J, Skovlund E, Christensen H, Jansson-Löfmark R, Åsberg A, Molden E, Robertsen I. Eide Kvitne K, et al. Among authors: christensen h. Eur J Clin Pharmacol. 2022 Aug;78(8):1289-1299. doi: 10.1007/s00228-022-03336-9. Epub 2022 Jun 1. Eur J Clin Pharmacol. 2022. PMID: 35648149 Free PMC article.

2

Diltiazem modulates cyclosporin A induced renal hemodynamic effects but not its effect on plasma endothelin-1.

Asberg A, Christensen H, Hartmann A, Berg KJ. Asberg A, et al. Among authors: christensen h. Clin Transplant. 1998 Oct;12(5):363-70. Clin Transplant. 1998. PMID: 9787942

3

A simple and sensitive high-performance liquid chromatography assay of diltiazem and main metabolites in renal transplanted patients.

Christensen H, Carlson E, Asberg A, Schram L, Berg KJ. Christensen H, et al. Clin Chim Acta. 1999 May;283(1-2):63-75. doi: 10.1016/s0009-8981(99)00042-x. Clin Chim Acta. 1999. PMID: 10404732 Clinical Trial.

4

Pharmacokinetic interactions between microemulsion formulated cyclosporine A and diltiazem in renal transplant recipients.

Asberg A, Christensen H, Hartmann A, Carlson E, Molden E, Berg KJ. Asberg A, et al. Among authors: christensen h. Eur J Clin Pharmacol. 1999 Jul;55(5):383-7. doi: 10.1007/s002280050644. Eur J Clin Pharmacol. 1999. PMID: 10456488

5

Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro.

Molden E, Christensen H, Sund RB. Molden E, et al. Among authors: christensen h. Drug Metab Dispos. 2000 Feb;28(2):107-9. Drug Metab Dispos. 2000. PMID: 10640504

6

CYP2D6 is involved in O-demethylation of diltiazem. An in vitro study with transfected human liver cells.

Molden E, Asberg A, Christensen H. Molden E, et al. Among authors: christensen h. Eur J Clin Pharmacol. 2000 Nov;56(8):575-9. doi: 10.1007/s002280000182. Eur J Clin Pharmacol. 2000. PMID: 11151747

7

Desacetyl-diltiazem displays severalfold higher affinity to CYP2D6 compared with CYP3A4.

Molden E, Asberg A, Christensen H. Molden E, et al. Among authors: christensen h. Drug Metab Dispos. 2002 Jan;30(1):1-3. doi: 10.1124/dmd.30.1.1. Drug Metab Dispos. 2002. PMID: 11744603

8

Pharmacokinetics of diltiazem and its metabolites in relation to CYP2D6 genotype.

Molden E, Johansen PW, Bøe GH, Bergan S, Christensen H, Rugstad HE, Rootwelt H, Reubsaet L, Lehne G. Molden E, et al. Among authors: christensen h. Clin Pharmacol Ther. 2002 Sep;72(3):333-42. doi: 10.1067/mcp.2002.127396. Clin Pharmacol Ther. 2002. PMID: 12235455

9

Intake of grapefruit juice alters the metabolic pattern of cyclosporin A in renal transplant recipients.

Hermann M, Asberg A, Reubsaet JL, Sather S, Berg KJ, Christensen H. Hermann M, et al. Among authors: christensen h. Int J Clin Pharmacol Ther. 2002 Oct;40(10):451-6. doi: 10.5414/cpp40451. Int J Clin Pharmacol Ther. 2002. PMID: 12395977 Clinical Trial.

10

Coadministration of grapefruit juice increases systemic exposure of diltiazem in healthy volunteers.

Christensen H, Asberg A, Holmboe AB, Berg KJ. Christensen H, et al. Eur J Clin Pharmacol. 2002 Nov;58(8):515-20. doi: 10.1007/s00228-002-0516-8. Epub 2002 Oct 16. Eur J Clin Pharmacol. 2002. PMID: 12451428 Clinical Trial.

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