Dougherty BV - Search Results

1

Identifying metabolic adaptations characteristic of cardiotoxicity using paired transcriptomics and metabolomics data integrated with a computational model of heart metabolism.

Dougherty BV, Moore CJ, Rawls KD, Jenior ML, Chun B, Nagdas S, Saucerman JJ, Kolling GL, Wallqvist A, Papin JA. Dougherty BV, et al. PLoS Comput Biol. 2024 Feb 29;20(2):e1011919. doi: 10.1371/journal.pcbi.1011919. eCollection 2024 Feb. PLoS Comput Biol. 2024. PMID: 38422168 Free PMC article.

2

Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort.

Leibowitz BD, Dougherty BV, Bell JSK, Kapilivsky J, Michuda J, Sedgewick AJ, Munson WA, Chandra TA, Dry JR, Beaubier N, Igartua C, Taxter T. Leibowitz BD, et al. Among authors: dougherty bv. BMC Cancer. 2022 May 28;22(1):587. doi: 10.1186/s12885-022-09669-z. BMC Cancer. 2022. PMID: 35643464 Free PMC article.

3

Metabolomics as a Truly Translational Tool for Precision Medicine.

Schmidt JC, Dougherty BV, Beger RD, Jones DP, Schmidt MA, Mattes WB. Schmidt JC, et al. Among authors: dougherty bv. Int J Toxicol. 2021 Oct;40(5):413-426. doi: 10.1177/10915818211039436. Int J Toxicol. 2021. PMID: 34514887 Free PMC article. Review.

4

Feelings of safety during daytime walking: associations with mental health, physical activity and cardiometabolic health in high vacancy, low-income neighborhoods in Detroit, Michigan.

Pearson AL, Clevenger KA, Horton TH, Gardiner JC, Asana V, Dougherty BV, Pfeiffer KA. Pearson AL, et al. Among authors: dougherty bv. Int J Health Geogr. 2021 May 3;20(1):19. doi: 10.1186/s12942-021-00271-3. Int J Health Geogr. 2021. PMID: 33941196 Free PMC article.

5

Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model.

Dougherty BV, Rawls KD, Kolling GL, Vinnakota KC, Wallqvist A, Papin JA. Dougherty BV, et al. Cell Rep. 2021 Mar 9;34(10):108836. doi: 10.1016/j.celrep.2021.108836. Cell Rep. 2021. PMID: 33691118 Free article.

6

Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model.

Rawls KD, Dougherty BV, Vinnakota KC, Pannala VR, Wallqvist A, Kolling GL, Papin JA. Rawls KD, et al. Among authors: dougherty bv. Toxicol Appl Pharmacol. 2021 Feb 1;412:115390. doi: 10.1016/j.taap.2020.115390. Epub 2020 Dec 31. Toxicol Appl Pharmacol. 2021. PMID: 33387578 Free PMC article.

7

Transcriptome-guided parsimonious flux analysis improves predictions with metabolic networks in complex environments.

Jenior ML, Moutinho TJ Jr, Dougherty BV, Papin JA. Jenior ML, et al. Among authors: dougherty bv. PLoS Comput Biol. 2020 Apr 16;16(4):e1007099. doi: 10.1371/journal.pcbi.1007099. eCollection 2020 Apr. PLoS Comput Biol. 2020. PMID: 32298268 Free PMC article.

8

Metabolic Network Reconstructions to Predict Drug Targets and Off-Target Effects.

Rawls K, Dougherty BV, Papin J. Rawls K, et al. Among authors: dougherty bv. Methods Mol Biol. 2020;2088:315-330. doi: 10.1007/978-1-0716-0159-4_14. Methods Mol Biol. 2020. PMID: 31893380 Review.

9

Genome-Scale Characterization of Toxicity-Induced Metabolic Alterations in Primary Hepatocytes.

Rawls KD, Blais EM, Dougherty BV, Vinnakota KC, Pannala VR, Wallqvist A, Kolling GL, Papin JA. Rawls KD, et al. Among authors: dougherty bv. Toxicol Sci. 2019 Dec 1;172(2):279-291. doi: 10.1093/toxsci/kfz197. Toxicol Sci. 2019. PMID: 31501904 Free PMC article.

10

A simplified metabolic network reconstruction to promote understanding and development of flux balance analysis tools.

Rawls KD, Dougherty BV, Blais EM, Stancliffe E, Kolling GL, Vinnakota K, Pannala VR, Wallqvist A, Papin JA. Rawls KD, et al. Among authors: dougherty bv. Comput Biol Med. 2019 Feb;105:64-71. doi: 10.1016/j.compbiomed.2018.12.010. Epub 2018 Dec 17. Comput Biol Med. 2019. PMID: 30584952 Free article.

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