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The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature.
Correy GJ, Kneller DW, Phillips G, Pant S, Russi S, Cohen AE, Meigs G, Holton JM, Gahbauer S, Thompson MC, Ashworth A, Coates L, Kovalevsky A, Meilleur F, Fraser JS. Correy GJ, et al. Among authors: meigs g. Sci Adv. 2022 May 27;8(21):eabo5083. doi: 10.1126/sciadv.abo5083. Epub 2022 May 27. Sci Adv. 2022. PMID: 35622909 Free PMC article.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Carvalho Martins L, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT; QCRG Structural Biology Consortium; Aimon A, Bennett JM, Brandao Neto J, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs MR, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ, Rack JGM, Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, O'Brien P, Jura N, Ashworth A, Irwin JJ, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. Schuller M, et al. Among authors: meigs g. Sci Adv. 2021 Apr 14;7(16):eabf8711. doi: 10.1126/sciadv.abf8711. Print 2021 Apr. Sci Adv. 2021. PMID: 33853786 Free PMC article.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Martins LC, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT; QCRG Structural Biology Consortium; Aimon A, Bennett JM, Neto JB, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs M, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ; Johannes Gregor Matthias Rack; Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, Jura N, Ashworth A, Irwin J, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. Schuller M, et al. Among authors: meigs g. bioRxiv [Preprint]. 2020 Nov 24:2020.11.24.393405. doi: 10.1101/2020.11.24.393405. bioRxiv. 2020. Update in: Sci Adv. 2021 Apr 14;7(16):eabf8711. doi: 10.1126/sciadv.abf8711. PMID: 33269349 Free PMC article. Updated. Preprint.
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source.
Classen S, Hura GL, Holton JM, Rambo RP, Rodic I, McGuire PJ, Dyer K, Hammel M, Meigs G, Frankel KA, Tainer JA. Classen S, et al. Among authors: meigs g. J Appl Crystallogr. 2013 Feb 1;46(Pt 1):1-13. doi: 10.1107/S0021889812048698. Epub 2013 Jan 17. J Appl Crystallogr. 2013. PMID: 23396808 Free PMC article.
Suite of three protein crystallography beamlines with single superconducting bend magnet as the source.
MacDowell AA, Celestre RS, Howells M, McKinney W, Krupnick J, Cambie D, Domning EE, Duarte RM, Kelez N, Plate DW, Cork CW, Earnest TN, Dickert J, Meigs G, Ralston C, Holton JM, Alber T, Berger JM, Agard DA, Padmore HA. MacDowell AA, et al. Among authors: meigs g. J Synchrotron Radiat. 2004 Nov 1;11(Pt 6):447-55. doi: 10.1107/S0909049504024835. Epub 2004 Oct 22. J Synchrotron Radiat. 2004. PMID: 15496731 Free article.
Reduced fire severity offers near-term buffer to climate-driven declines in conifer resilience across the western United States.
Davis KT, Robles MD, Kemp KB, Higuera PE, Chapman T, Metlen KL, Peeler JL, Rodman KC, Woolley T, Addington RN, Buma BJ, Cansler CA, Case MJ, Collins BM, Coop JD, Dobrowski SZ, Gill NS, Haffey C, Harris LB, Harvey BJ, Haugo RD, Hurteau MD, Kulakowski D, Littlefield CE, McCauley LA, Povak N, Shive KL, Smith E, Stevens JT, Stevens-Rumann CS, Taylor AH, Tepley AJ, Young DJN, Andrus RA, Battaglia MA, Berkey JK, Busby SU, Carlson AR, Chambers ME, Dodson EK, Donato DC, Downing WM, Fornwalt PJ, Halofsky JS, Hoffman A, Holz A, Iniguez JM, Krawchuk MA, Kreider MR, Larson AJ, Meigs GW, Roccaforte JP, Rother MT, Safford H, Schaedel M, Sibold JS, Singleton MP, Turner MG, Urza AK, Clark-Wolf KD, Yocom L, Fontaine JB, Campbell JL. Davis KT, et al. Among authors: meigs gw. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2208120120. doi: 10.1073/pnas.2208120120. Epub 2023 Mar 6. Proc Natl Acad Sci U S A. 2023. PMID: 36877837 Free PMC article.
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature.
Correy GJ, Kneller DW, Phillips G, Pant S, Russi S, Cohen AE, Meigs G, Holton JM, Gahbauer S, Thompson MC, Ashworth A, Coates L, Kovalevsky A, Meilleur F, Fraser JS. Correy GJ, et al. Among authors: meigs g. bioRxiv [Preprint]. 2022 Feb 9:2022.02.07.479477. doi: 10.1101/2022.02.07.479477. bioRxiv. 2022. Update in: Sci Adv. 2022 May 27;8(21):eabo5083. doi: 10.1126/sciadv.abo5083. PMID: 35169801 Free PMC article. Updated. Preprint.
Natural disturbance impacts on trade-offs and co-benefits of forest biodiversity and carbon.
Mikoláš M, Svitok M, Bače R, Meigs GW, Keeton WS, Keith H, Buechling A, Trotsiuk V, Kozák D, Bollmann K, Begovič K, Čada V, Chaskovskyy O, Ralhan D, Dušátko M, Ferenčík M, Frankovič M, Gloor R, Hofmeister J, Janda P, Kameniar O, Lábusová J, Majdanová L, Nagel TA, Pavlin J, Pettit JL, Rodrigo R, Roibu CC, Rydval M, Sabatini FM, Schurman J, Synek M, Vostarek O, Zemlerová V, Svoboda M. Mikoláš M, et al. Among authors: meigs gw. Proc Biol Sci. 2021 Oct 27;288(1961):20211631. doi: 10.1098/rspb.2021.1631. Epub 2021 Oct 20. Proc Biol Sci. 2021. PMID: 34666524 Free PMC article.
39 results