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Page 1
Human NLRP1 is a sensor of pathogenic coronavirus 3CL proteases in lung epithelial cells.
Planès R, Pinilla M, Santoni K, Hessel A, Passemar C, Lay K, Paillette P, Valadão AC, Robinson KS, Bastard P, Lam N, Fadrique R, Rossi I, Pericat D, Bagayoko S, Leon-Icaza SA, Rombouts Y, Perouzel E, Tiraby M; COVID Human Genetic Effort; Zhang Q, Cicuta P, Jouanguy E, Neyrolles O, Bryant CE, Floto AR, Goujon C, Lei FZ, Martin-Blondel G, Silva S, Casanova JL, Cougoule C, Reversade B, Marcoux J, Ravet E, Meunier E. Planès R, et al. Among authors: leon icaza sa. Mol Cell. 2022 Jul 7;82(13):2385-2400.e9. doi: 10.1016/j.molcel.2022.04.033. Epub 2022 May 16. Mol Cell. 2022. PMID: 35594856 Free PMC article.
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa.
Santoni K, Pericat D, Gorse L, Buyck J, Pinilla M, Prouvensier L, Bagayoko S, Hessel A, Leon-Icaza SA, Bellard E, Mazères S, Doz-Deblauwe E, Winter N, Paget C, Girard JP, Pham CTN, Cougoule C, Poincloux R, Lamkanfi M, Lefrançais E, Meunier E, Planès R. Santoni K, et al. Among authors: leon icaza sa. PLoS Pathog. 2022 Jul 18;18(7):e1010305. doi: 10.1371/journal.ppat.1010305. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35849616 Free PMC article.
Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
Bagayoko S, Leon-Icaza SA, Pinilla M, Hessel A, Santoni K, Péricat D, Bordignon PJ, Moreau F, Eren E, Boyancé A, Naser E, Lefèvre L, Berrone C, Iakobachvili N, Metais A, Rombouts Y, Lugo-Villarino G, Coste A, Attrée I, Frank DW, Clevers H, Peters PJ, Cougoule C, Planès R, Meunier E. Bagayoko S, et al. Among authors: leon icaza sa. PLoS Pathog. 2021 Sep 13;17(9):e1009927. doi: 10.1371/journal.ppat.1009927. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34516571 Free PMC article.
Mycobacteria-host interactions in human bronchiolar airway organoids.
Iakobachvili N, Leon-Icaza SA, Knoops K, Sachs N, Mazères S, Simeone R, Peixoto A, Bernard C, Murris-Espin M, Mazières J, Cam K, Chalut C, Guilhot C, López-Iglesias C, Ravelli RBG, Neyrolles O, Meunier E, Lugo-Villarino G, Clevers H, Cougoule C, Peters PJ. Iakobachvili N, et al. Among authors: leon icaza sa. Mol Microbiol. 2022 Mar;117(3):682-692. doi: 10.1111/mmi.14824. Epub 2021 Nov 5. Mol Microbiol. 2022. PMID: 34605588 Free PMC article.
A Pulmonary Lactobacillus murinus Strain Induces Th17 and RORγt+ Regulatory T Cells and Reduces Lung Inflammation in Tuberculosis.
Bernard-Raichon L, Colom A, Monard SC, Namouchi A, Cescato M, Garnier H, Leon-Icaza SA, Métais A, Dumas A, Corral D, Ghebrendrias N, Guilloton P, Vérollet C, Hudrisier D, Remot A, Langella P, Thomas M, Cougoule C, Neyrolles O, Lugo-Villarino G. Bernard-Raichon L, et al. J Immunol. 2021 Oct 1;207(7):1857-1870. doi: 10.4049/jimmunol.2001044. Epub 2021 Sep 3. J Immunol. 2021. PMID: 34479945
Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA.
Alcaraz M, Roquet-Banères F, Leon-Icaza SA, Abendroth J, Boudehen YM, Cougoule C, Edwards TE, Kremer L. Alcaraz M, et al. Among authors: leon icaza sa. ACS Infect Dis. 2022 Oct 14;8(10):2171-2186. doi: 10.1021/acsinfecdis.2c00314. Epub 2022 Sep 15. ACS Infect Dis. 2022. PMID: 36107992 Free article.
Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death.
Delehouzé C, Comte A, Leon-Icaza SA, Cougoule C, Hauteville M, Goekjian P, Bulinski JC, Dimanche-Boitrel MT, Meunier E, Rousselot M, Bach S. Delehouzé C, et al. Among authors: leon icaza sa. Sci Rep. 2022 Mar 24;12(1):5118. doi: 10.1038/s41598-022-09019-w. Sci Rep. 2022. PMID: 35332201 Free PMC article.
EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption.
Pinilla M, Mazars R, Vergé R, Gorse L, Paradis M, Suire B, Santoni K, Robinson KS, Toh GA, Prouvensier L, Leon-Icaza SA, Hessel A, Péricat D, Murris M, Guet-Revillet H, Henras A, Buyck J, Ravet E, Zhong FL, Cougoule C, Planès R, Meunier E. Pinilla M, et al. Among authors: leon icaza sa. J Exp Med. 2023 Oct 2;220(10):e20230104. doi: 10.1084/jem.20230104. Epub 2023 Aug 29. J Exp Med. 2023. PMID: 37642996 Free PMC article.
Druggable redox pathways against Mycobacterium abscessus in cystic fibrosis patient-derived airway organoids.
Leon-Icaza SA, Bagayoko S, Vergé R, Iakobachvili N, Ferrand C, Aydogan T, Bernard C, Sanchez Dafun A, Murris-Espin M, Mazières J, Bordignon PJ, Mazères S, Bernes-Lasserre P, Ramé V, Lagarde JM, Marcoux J, Bousquet MP, Chalut C, Guilhot C, Clevers H, Peters PJ, Molle V, Lugo-Villarino G, Cam K, Berry L, Meunier E, Cougoule C. Leon-Icaza SA, et al. PLoS Pathog. 2023 Aug 24;19(8):e1011559. doi: 10.1371/journal.ppat.1011559. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37619220 Free PMC article.
Establishing 20S Proteasome Genetic, Translational and Post-Translational Status from Precious Biological and Patient Samples with Top-Down MS.
Dafun AS, Živković D, Leon-Icaza SA, Möller S, Froment C, Bonnet D, de Jesus AA, Alric L, Quaranta-Nicaise M, Ferrand A, Cougoule C, Meunier E, Burlet-Schiltz O, Ebstein F, Goldbach-Mansky R, Krüger E, Bousquet MP, Marcoux J. Dafun AS, et al. Among authors: leon icaza sa. Cells. 2023 Mar 8;12(6):844. doi: 10.3390/cells12060844. Cells. 2023. PMID: 36980185 Free PMC article.
12 results