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Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Soflaee MH, Kesavan R, Sahu U, Tasdogan A, Villa E, Djabari Z, Cai F, Tran DH, Vu HS, Ali ES, Rion H, O'Hara BP, Kelekar S, Hallett JH, Martin M, Mathews TP, Gao P, Asara JM, Manning BD, Ben-Sahra I, Hoxhaj G. Soflaee MH, et al. Among authors: mathews tp. Nat Commun. 2022 May 16;13(1):2698. doi: 10.1038/s41467-022-30362-z. Nat Commun. 2022. PMID: 35577785 Free PMC article.
Metabolic heterogeneity confers differences in melanoma metastatic potential.
Tasdogan A, Faubert B, Ramesh V, Ubellacker JM, Shen B, Solmonson A, Murphy MM, Gu Z, Gu W, Martin M, Kasitinon SY, Vandergriff T, Mathews TP, Zhao Z, Schadendorf D, DeBerardinis RJ, Morrison SJ. Tasdogan A, et al. Among authors: mathews tp. Nature. 2020 Jan;577(7788):115-120. doi: 10.1038/s41586-019-1847-2. Epub 2019 Dec 18. Nature. 2020. PMID: 31853067 Free PMC article.
Lymph protects metastasizing melanoma cells from ferroptosis.
Ubellacker JM, Tasdogan A, Ramesh V, Shen B, Mitchell EC, Martin-Sandoval MS, Gu Z, McCormick ML, Durham AB, Spitz DR, Zhao Z, Mathews TP, Morrison SJ. Ubellacker JM, et al. Among authors: mathews tp. Nature. 2020 Sep;585(7823):113-118. doi: 10.1038/s41586-020-2623-z. Epub 2020 Aug 19. Nature. 2020. PMID: 32814895 Free PMC article.
Stable isotope tracing to assess tumor metabolism in vivo.
Faubert B, Tasdogan A, Morrison SJ, Mathews TP, DeBerardinis RJ. Faubert B, et al. Among authors: mathews tp. Nat Protoc. 2021 Nov;16(11):5123-5145. doi: 10.1038/s41596-021-00605-2. Epub 2021 Sep 17. Nat Protoc. 2021. PMID: 34535790 Free PMC article. Review.
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells.
Aurora AB, Khivansara V, Leach A, Gill JG, Martin-Sandoval M, Yang C, Kasitinon SY, Bezwada D, Tasdogan A, Gu W, Mathews TP, Zhao Z, DeBerardinis RJ, Morrison SJ. Aurora AB, et al. Among authors: mathews tp. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120617119. doi: 10.1073/pnas.2120617119. Proc Natl Acad Sci U S A. 2022. PMID: 35110412 Free PMC article.
Compartmentalized metabolism supports midgestation mammalian development.
Solmonson A, Faubert B, Gu W, Rao A, Cowdin MA, Menendez-Montes I, Kelekar S, Rogers TJ, Pan C, Guevara G, Tarangelo A, Zacharias LG, Martin-Sandoval MS, Do D, Pachnis P, Dumesnil D, Mathews TP, Tasdogan A, Pham A, Cai L, Zhao Z, Ni M, Cleaver O, Sadek HA, Morrison SJ, DeBerardinis RJ. Solmonson A, et al. Among authors: mathews tp. Nature. 2022 Apr;604(7905):349-353. doi: 10.1038/s41586-022-04557-9. Epub 2022 Apr 6. Nature. 2022. PMID: 35388219 Free PMC article.
48 results