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Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway.
Soflaee MH, Kesavan R, Sahu U, Tasdogan A, Villa E, Djabari Z, Cai F, Tran DH, Vu HS, Ali ES, Rion H, O'Hara BP, Kelekar S, Hallett JH, Martin M, Mathews TP, Gao P, Asara JM, Manning BD, Ben-Sahra I, Hoxhaj G. Soflaee MH, et al. Nat Commun. 2022 May 16;13(1):2698. doi: 10.1038/s41467-022-30362-z. Nat Commun. 2022. PMID: 35577785 Free PMC article.
The TSC-mTOR pathway regulates macrophage polarization.
Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. Byles V, et al. Nat Commun. 2013;4:2834. doi: 10.1038/ncomms3834. Nat Commun. 2013. PMID: 24280772 Free PMC article.
mTORC1 signaling and the metabolic control of cell growth.
Ben-Sahra I, Manning BD. Ben-Sahra I, et al. Curr Opin Cell Biol. 2017 Apr;45:72-82. doi: 10.1016/j.ceb.2017.02.012. Epub 2017 Apr 12. Curr Opin Cell Biol. 2017. PMID: 28411448 Free PMC article. Review.
70 results