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Oxysterols and nuclear receptors.
Ma L, Nelson ER. Ma L, et al. Mol Cell Endocrinol. 2019 Mar 15;484:42-51. doi: 10.1016/j.mce.2019.01.016. Epub 2019 Jan 18. Mol Cell Endocrinol. 2019. PMID: 30660701 Review.
Host CYP27A1 expression is essential for ovarian cancer progression.
He S, Ma L, Baek AE, Vardanyan A, Vembar V, Chen JJ, Nelson AT, Burdette JE, Nelson ER. He S, et al. Among authors: ma l. Endocr Relat Cancer. 2019 Jul;26(7):659-675. doi: 10.1530/ERC-18-0572. Endocr Relat Cancer. 2019. PMID: 31048561 Free PMC article.
Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer.
Hutchinson SA, Websdale A, Cioccoloni G, Røberg-Larsen H, Lianto P, Kim B, Rose A, Soteriou C, Pramanik A, Wastall LM, Williams BJ, Henn MA, Chen JJ, Ma L, Moore JB, Nelson E, Hughes TA, Thorne JL. Hutchinson SA, et al. Among authors: ma l. Oncogene. 2021 Apr;40(16):2872-2883. doi: 10.1038/s41388-021-01720-w. Epub 2021 Mar 19. Oncogene. 2021. PMID: 33742124 Free PMC article.
The Cholesterol Metabolite 27HC Increases Secretion of Extracellular Vesicles Which Promote Breast Cancer Progression.
Baek AE, Krawczynska N, Das Gupta A, Dvoretskiy SV, You S, Park J, Deng YH, Sorrells JE, Smith BP, Ma L, Nelson AT, McDowell HB, Sprenger A, Henn MA, Madak-Erdogan Z, Kong H, Boppart SA, Boppart MD, Nelson ER. Baek AE, et al. Among authors: ma l. Endocrinology. 2021 Jul 1;162(7):bqab095. doi: 10.1210/endocr/bqab095. Endocrinology. 2021. PMID: 33959755 Free PMC article.
The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer.
Nelczyk AT, Ma L, Gupta AD, Gamage HEV, McHenry MT, Henn MA, Kadiri M, Wang Y, Krawczynska N, Bendre S, He S, Shahoei SH, Madak-Erdogan Z, Hsiao SH, Saleh T, Carpenter V, Gewirtz DA, Spinella MJ, Nelson ER. Nelczyk AT, et al. Among authors: ma l. Biochim Biophys Acta Mol Basis Dis. 2022 Nov 1;1868(11):166515. doi: 10.1016/j.bbadis.2022.166515. Epub 2022 Aug 4. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35932893 Free PMC article.
Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice.
Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh HH, Weinstock A, Khan S, Ma L, Durán JGB, McDonald J, Nelson ER, Park S, McDonnell DP, Moore KJ, Huang LJ, Fisher EA, Mineo C, Huang L, Shaul PW. Yu L, et al. Among authors: ma l. Nat Commun. 2023 Jul 25;14(1):4101. doi: 10.1038/s41467-023-39586-z. Nat Commun. 2023. PMID: 37491347 Free PMC article.
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