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A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice.
Liu L, Chen T, Zhou L, Sun J, Li Y, Nie M, Xiong H, Zhu Y, Xue W, Wu Y, Li T, Zhang T, Kong Z, Yu H, Zhang J, Gu Y, Zheng Q, Zhao Q, Xia N, Li S. Liu L, et al. Among authors: chen t. Front Microbiol. 2022 Apr 26;13:854630. doi: 10.3389/fmicb.2022.854630. eCollection 2022. Front Microbiol. 2022. PMID: 35558112 Free PMC article.
SARS-CoV-2 spike produced in insect cells elicits high neutralization titres in non-human primates.
Li T, Zheng Q, Yu H, Wu D, Xue W, Xiong H, Huang X, Nie M, Yue M, Rong R, Zhang S, Zhang Y, Wu Y, Wang S, Zha Z, Chen T, Deng T, Wang Y, Zhang T, Chen Y, Yuan Q, Zhao Q, Zhang J, Gu Y, Li S, Xia N. Li T, et al. Among authors: chen t, chen y. Emerg Microbes Infect. 2020 Dec;9(1):2076-2090. doi: 10.1080/22221751.2020.1821583. Emerg Microbes Infect. 2020. PMID: 32897177 Free PMC article.
Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Li T, Xue W, Zheng Q, Song S, Yang C, Xiong H, Zhang S, Hong M, Zhang Y, Yu H, Zhang Y, Sun H, Huang Y, Deng T, Chi X, Li J, Wang S, Zhou L, Chen T, Wang Y, Cheng T, Zhang T, Yuan Q, Zhao Q, Zhang J, McLellan JS, Zhou ZH, Zhang Z, Li S, Gu Y, Xia N. Li T, et al. Among authors: chen t. Nat Commun. 2021 Sep 27;12(1):5652. doi: 10.1038/s41467-021-25997-3. Nat Commun. 2021. PMID: 34580306 Free PMC article.
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