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Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection.
Hollenhorst MI, Nandigama R, Evers SB, Gamayun I, Abdel Wadood N, Salah A, Pieper M, Wyatt A, Stukalov A, Gebhardt A, Nadolni W, Burow W, Herr C, Beisswenger C, Kusumakshi S, Ectors F, Kichko TI, Hübner L, Reeh P, Munder A, Wienhold SM, Witzenrath M, Bals R, Flockerzi V, Gudermann T, Bischoff M, Lipp P, Zierler S, Chubanov V, Pichlmair A, König P, Boehm U, Krasteva-Christ G. Hollenhorst MI, et al. Among authors: pichlmair a. J Clin Invest. 2022 Jul 1;132(13):e150951. doi: 10.1172/JCI150951. J Clin Invest. 2022. PMID: 35503420 Free PMC article.
Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.
Gruber C, Krautner L, Bergant V, Grass V, Ma Z, Rheinemann L, Krus A, Reinhardt F, Mazneykova L, Rocha-Hasler M, Truong DJ, Westmeyer GG, Pichlmair A, Ebert G, Giesert F, Wurst W. Gruber C, et al. Among authors: pichlmair a. Cell Discov. 2024 Apr 12;10(1):42. doi: 10.1038/s41421-024-00672-1. Cell Discov. 2024. PMID: 38609360 Free PMC article. No abstract available.
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication.
Tsukamoto Y, Hiono T, Yamada S, Matsuno K, Faist A, Claff T, Hou J, Namasivayam V, Vom Hemdt A, Sugimoto S, Ng JY, Christensen MH, Tesfamariam YM, Wolter S, Juranek S, Zillinger T, Bauer S, Hirokawa T, Schmidt FI, Kochs G, Shimojima M, Huang YS, Pichlmair A, Kümmerer BM, Sakoda Y, Schlee M, Brunotte L, Müller CE, Igarashi M, Kato H. Tsukamoto Y, et al. Among authors: pichlmair a. Science. 2023 Feb 10;379(6632):586-591. doi: 10.1126/science.add0875. Epub 2023 Feb 9. Science. 2023. PMID: 36758070
mRNA 3'UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus.
Bergant V, Schnepf D, de Andrade Krätzig N, Hubel P, Urban C, Engleitner T, Dijkman R, Ryffel B, Steiger K, Knolle PA, Kochs G, Rad R, Staeheli P, Pichlmair A. Bergant V, et al. Among authors: pichlmair a. Nat Commun. 2023 Aug 15;14(1):4906. doi: 10.1038/s41467-023-40469-6. Nat Commun. 2023. PMID: 37582777 Free PMC article.
Gambling with Flu: "All in" to Maximize Reward.
Stukalov A, Pichlmair A. Stukalov A, et al. Among authors: pichlmair a. Cell Host Microbe. 2015 Dec 9;18(6):643-5. doi: 10.1016/j.chom.2015.11.010. Cell Host Microbe. 2015. PMID: 26651939 Free article.
Discrimination of Self and Non-Self Ribonucleic Acids.
Gebhardt A, Laudenbach BT, Pichlmair A. Gebhardt A, et al. Among authors: pichlmair a. J Interferon Cytokine Res. 2017 May;37(5):184-197. doi: 10.1089/jir.2016.0092. J Interferon Cytokine Res. 2017. PMID: 28475460 Free PMC article. Review.
The alternative cap-binding complex is required for antiviral defense in vivo.
Gebhardt A, Bergant V, Schnepf D, Moser M, Meiler A, Togbe D, Mackowiak C, Reinert LS, Paludan SR, Ryffel B, Stukalov A, Staeheli P, Pichlmair A. Gebhardt A, et al. Among authors: pichlmair a. PLoS Pathog. 2019 Dec 19;15(12):e1008155. doi: 10.1371/journal.ppat.1008155. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31856218 Free PMC article.
93 results