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In situ identification of cellular drug targets in mammalian tissue.
Cell. 2022 May 12;185(10):1793-1805.e17. doi: 10.1016/j.cell.2022.03.040. Epub 2022 Apr 27.
Cell. 2022.
PMID: 35483372
Free PMC article.
Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators.
Clapper JR, Henry CL, Niphakis MJ, Knize AM, Coppola AR, Simon GM, Ngo N, Herbst RA, Herbst DM, Reed AW, Cisar JS, Weber OD, Viader A, Alexander JP, Cunningham ML, Jones TK, Fraser IP, Grice CA, Ezekowitz RAB, O'Neill GP, Blankman JL.
Clapper JR, et al. Among authors: herbst dm.
J Pharmacol Exp Ther. 2018 Dec;367(3):494-508. doi: 10.1124/jpet.118.252296. Epub 2018 Oct 10.
J Pharmacol Exp Ther. 2018.
PMID: 30305428
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Phospholipase Cγ2 regulates endocannabinoid and eicosanoid networks in innate immune cells.
Jing H, Reed A, Ulanovskaya OA, Grigoleit JS, Herbst DM, Henry CL, Li H, Barbas S, Germain J, Masuda K, Cravatt BF.
Jing H, et al. Among authors: herbst dm.
Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2112971118. doi: 10.1073/pnas.2112971118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34607960
Free PMC article.
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Quantification of In Vivo Target Engagement Using Microfluidic Activity-Based Protein Profiling.
Reardon HT, Herbst RA, Henry CL, Herbst DM, Ngo N, Cisar JS, Weber OD, Niphakis MJ, O'Neill GP.
Reardon HT, et al. Among authors: herbst dm.
SLAS Technol. 2019 Oct;24(5):489-498. doi: 10.1177/2472630319852303. Epub 2019 Jun 14.
SLAS Technol. 2019.
PMID: 31199699
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Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels.
Yan S, Santoro A, Niphakis MJ, Pinto AM, Jacobs CL, Ahmad R, Suciu RM, Fonslow BR, Herbst-Graham RA, Ngo N, Henry CL, Herbst DM, Saghatelian A, Kahn BB, Rosen ED.
Yan S, et al. Among authors: herbst dm.
Nat Commun. 2024 May 30;15(1):4605. doi: 10.1038/s41467-024-48220-5.
Nat Commun. 2024.
PMID: 38816388
Free PMC article.
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