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Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis.
Kunnumakkara AB, Nair AS, Ahn KS, Pandey MK, Yi Z, Liu M, Aggarwal BB. Kunnumakkara AB, et al. Among authors: liu m. Blood. 2007 Jun 15;109(12):5112-21. doi: 10.1182/blood-2007-01-067256. Epub 2007 Mar 1. Blood. 2007. PMID: 17332240 Free PMC article.
Regulation of bone formation and remodeling by G-protein-coupled receptor 48.
Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Höök M, Liu M. Luo J, et al. Among authors: liu m. Development. 2009 Aug;136(16):2747-56. doi: 10.1242/dev.033571. Epub 2009 Jul 15. Development. 2009. PMID: 19605502 Free PMC article.
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