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The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses.
Serrero MC, Girault V, Weigang S, Greco TM, Ramos-Nascimento A, Anderson F, Piras A, Hickford Martinez A, Hertzog J, Binz A, Pohlmann A, Prank U, Rehwinkel J, Bauerfeind R, Cristea IM, Pichlmair A, Kochs G, Sodeik B. Serrero MC, et al. Among authors: rehwinkel j. Elife. 2022 Apr 27;11:e76804. doi: 10.7554/eLife.76804. Elife. 2022. PMID: 35475759 Free PMC article.
Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.
Hertzog J, Dias Junior AG, Rigby RE, Donald CL, Mayer A, Sezgin E, Song C, Jin B, Hublitz P, Eggeling C, Kohl A, Rehwinkel J. Hertzog J, et al. Among authors: rehwinkel j. Eur J Immunol. 2018 Jul;48(7):1120-1136. doi: 10.1002/eji.201847483. Epub 2018 Apr 6. Eur J Immunol. 2018. PMID: 29572905 Free PMC article.
Regulation and inhibition of the DNA sensor cGAS.
Hertzog J, Rehwinkel J. Hertzog J, et al. Among authors: rehwinkel j. EMBO Rep. 2020 Dec 3;21(12):e51345. doi: 10.15252/embr.202051345. Epub 2020 Nov 5. EMBO Rep. 2020. PMID: 33155371 Free PMC article. Review.
The RNA sensor MDA5 detects SARS-CoV-2 infection.
Sampaio NG, Chauveau L, Hertzog J, Bridgeman A, Fowler G, Moonen JP, Dupont M, Russell RA, Noerenberg M, Rehwinkel J. Sampaio NG, et al. Among authors: rehwinkel j. Sci Rep. 2021 Jul 1;11(1):13638. doi: 10.1038/s41598-021-92940-3. Sci Rep. 2021. PMID: 34211037 Free PMC article.
Varicella-Zoster virus ORF9 is an antagonist of the DNA sensor cGAS.
Hertzog J, Zhou W, Fowler G, Rigby RE, Bridgeman A, Blest HT, Cursi C, Chauveau L, Davenne T, Warner BE, Kinchington PR, Kranzusch PJ, Rehwinkel J. Hertzog J, et al. Among authors: rehwinkel j. EMBO J. 2022 Jul 18;41(14):e109217. doi: 10.15252/embj.2021109217. Epub 2022 Jun 7. EMBO J. 2022. PMID: 35670106 Free PMC article.
HSV-1 employs UL56 to antagonize expression and function of cGAMP channels.
Blest HTW, Redmond A, Avissar J, Barker J, Bridgeman A, Fowler G, Chauveau L, Hertzog J, Vendrell I, Fischer R, Iversen MB, Jing L, Koelle DM, Paludan SR, Kessler BM, Crump CM, Rehwinkel J. Blest HTW, et al. Among authors: rehwinkel j. Cell Rep. 2024 May 28;43(5):114122. doi: 10.1016/j.celrep.2024.114122. Epub 2024 Apr 22. Cell Rep. 2024. PMID: 38652659 Free article.
94 results