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KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming.
Na F, Pan X, Chen J, Chen X, Wang M, Chi P, You L, Zhang L, Zhong A, Zhao L, Dai S, Zhang M, Wang Y, Wang B, Zheng J, Wang Y, Xu J, Wang J, Wu B, Chen M, Liu H, Xue J, Huang M, Gong Y, Zhu J, Zhou L, Zhang Y, Yu M, Tian P, Fan M, Lu Z, Xue Z, Zhao Y, Yang H, Zhao C, Wang Y, Han J, Yang S, Xie D, Chen L, Zhong Q, Zeng M, Lowe SW, Lu Y, Liu Y, Wei Y, Chen C. Na F, et al. Among authors: chen j, chen l, chen m, chen c, chen x. Nat Cancer. 2022 Jun;3(6):753-767. doi: 10.1038/s43018-022-00361-6. Epub 2022 Apr 21. Nat Cancer. 2022. PMID: 35449309 Free PMC article.
Characteristics of genomic alterations of lung adenocarcinoma in young never-smokers.
Luo W, Tian P, Wang Y, Xu H, Chen L, Tang C, Shu Y, Zhang S, Wang Z, Zhang J, Zhang L, Jiang L, Liu L, Che G, Guo C, Zhang H, Wang J, Li W. Luo W, et al. Among authors: chen l. Int J Cancer. 2018 Oct 1;143(7):1696-1705. doi: 10.1002/ijc.31542. Epub 2018 May 7. Int J Cancer. 2018. PMID: 29667179 Free PMC article.
An Epigenetic Mechanism Underlying Chromosome 17p Deletion-Driven Tumorigenesis.
Chen M, Chen X, Li S, Pan X, Gong Y, Zheng J, Xu J, Zhao C, Zhang Q, Zhang S, Qi L, Wang Z, Shi K, Ding BS, Xue Z, Chen L, Yang S, Wang Y, Niu T, Dai L, Lowe SW, Chen C, Liu Y. Chen M, et al. Among authors: chen l, chen c, chen x. Cancer Discov. 2021 Jan;11(1):194-207. doi: 10.1158/2159-8290.CD-20-0336. Epub 2020 Sep 25. Cancer Discov. 2021. PMID: 32978226 Free PMC article.
Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma.
Wang X, Zhou R, Xiong Y, Zhou L, Yan X, Wang M, Li F, Xie C, Zhang Y, Huang Z, Ding C, Shi K, Li W, Liu Y, Cao Z, Zhang ZN, Zhou S, Chen C, Zhang Y, Chen L, Wang Y. Wang X, et al. Among authors: chen l, chen c. Cell Res. 2021 Jun;31(6):684-702. doi: 10.1038/s41422-020-00451-z. Epub 2021 Jan 4. Cell Res. 2021. PMID: 33390587 Free PMC article.
Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity.
Yang J, Wang W, Chen Z, Lu S, Yang F, Bi Z, Bao L, Mo F, Li X, Huang Y, Hong W, Yang Y, Zhao Y, Ye F, Lin S, Deng W, Chen H, Lei H, Zhang Z, Luo M, Gao H, Zheng Y, Gong Y, Jiang X, Xu Y, Lv Q, Li D, Wang M, Li F, Wang S, Wang G, Yu P, Qu Y, Yang L, Deng H, Tong A, Li J, Wang Z, Yang J, Shen G, Zhao Z, Li Y, Luo J, Liu H, Yu W, Yang M, Xu J, Wang J, Li H, Wang H, Kuang D, Lin P, Hu Z, Guo W, Cheng W, He Y, Song X, Chen C, Xue Z, Yao S, Chen L, Ma X, Chen S, Gou M, Huang W, Wang Y, Fan C, Tian Z, Shi M, Wang FS, Dai L, Wu M, Li G, Wang G, Peng Y, Qian Z, Huang C, Lau JY, Yang Z, Wei Y, Cen X, Peng X, Qin C, Zhang K, Lu G, Wei X. Yang J, et al. Among authors: chen z, chen l, chen c, chen s, chen h. Nature. 2021 Feb;590(7844):E23. doi: 10.1038/s41586-020-03108-4. Nature. 2021. PMID: 33469221 No abstract available.
Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer.
Zhang L, Zhang Y, Wang C, Yang Y, Ni Y, Wang Z, Song T, Yao M, Liu Z, Chao N, Yang Y, Shao J, Li Z, Zhou R, Chen L, Zhang D, Zhao Y, Liu W, Li Y, He P, Lin JW, Wang Y, Zhang K, Chen L, Li W. Zhang L, et al. Among authors: chen l. Signal Transduct Target Ther. 2022 Jan 14;7(1):9. doi: 10.1038/s41392-021-00824-9. Signal Transduct Target Ther. 2022. PMID: 35027529 Free PMC article.
Spatial transcriptomics reveals niche-specific enrichment and vulnerabilities of radial glial stem-like cells in malignant gliomas.
Ren Y, Huang Z, Zhou L, Xiao P, Song J, He P, Xie C, Zhou R, Li M, Dong X, Mao Q, You C, Xu J, Liu Y, Lan Z, Zhang T, Gan Q, Yang Y, Chen T, Huang B, Yang X, Xiao A, Ou Y, Su Z, Chen L, Zhang Y, Ju Y, Zhang Y, Wang Y. Ren Y, et al. Among authors: chen l, chen t. Nat Commun. 2023 Feb 23;14(1):1028. doi: 10.1038/s41467-023-36707-6. Nat Commun. 2023. PMID: 36823172 Free PMC article.
Capture of RNA-binding proteins across mouse tissues using HARD-AP.
Ren Y, Liao H, Yan J, Lu H, Mao X, Wang C, Li YF, Liu Y, Chen C, Chen L, Wang X, Zhou KY, Liu HM, Liu Y, Hua YM, Yu L, Xue Z. Ren Y, et al. Among authors: chen l, chen c. Nat Commun. 2024 Sep 28;15(1):8421. doi: 10.1038/s41467-024-52765-w. Nat Commun. 2024. PMID: 39341811 Free PMC article.
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