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AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration.
Tao Y, Liu X, Yang L, Chu C, Tan F, Yu Z, Ke J, Li X, Zheng X, Zhao X, Qi J, Lin CP, Chai R, Zhong G, Wu H. Tao Y, et al. Among authors: zhong g. Signal Transduct Target Ther. 2022 Apr 22;7(1):109. doi: 10.1038/s41392-022-00938-8. Signal Transduct Target Ther. 2022. PMID: 35449181 Free PMC article.
Critical role of spectrin in hearing development and deafness.
Liu Y, Qi J, Chen X, Tang M, Chu C, Zhu W, Li H, Tian C, Yang G, Zhong C, Zhang Y, Ni G, He S, Chai R, Zhong G. Liu Y, et al. Among authors: zhong c, zhong g. Sci Adv. 2019 Apr 17;5(4):eaav7803. doi: 10.1126/sciadv.aav7803. eCollection 2019 Apr. Sci Adv. 2019. PMID: 31001589 Free PMC article.
AAV-ie enables safe and efficient gene transfer to inner ear cells.
Tan F, Chu C, Qi J, Li W, You D, Li K, Chen X, Zhao W, Cheng C, Liu X, Qiao Y, Su B, He S, Zhong C, Li H, Chai R, Zhong G. Tan F, et al. Among authors: zhong c, zhong g. Nat Commun. 2019 Aug 19;10(1):3733. doi: 10.1038/s41467-019-11687-8. Nat Commun. 2019. PMID: 31427575 Free PMC article.
Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior.
Fan KQ, Li YY, Wang HL, Mao XT, Guo JX, Wang F, Huang LJ, Li YN, Ma XY, Gao ZJ, Chen W, Qian DD, Xue WJ, Cao Q, Zhang L, Shen L, Zhang L, Tong C, Zhong JY, Lu W, Lu L, Ren KM, Zhong G, Wang Y, Tang M, Feng XH, Chai RJ, Jin J. Fan KQ, et al. Among authors: zhong jy, zhong g. Cell. 2019 Oct 31;179(4):864-879.e19. doi: 10.1016/j.cell.2019.10.001. Cell. 2019. PMID: 31675497 Free article.
Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α2C Adrenergic Receptor.
Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, Hu T, Tao H, Sun Y, Song Y, Hu L, Liu ZJ, Stevens RC, Zhao S, Wu D, Zhong G. Chen X, et al. Among authors: zhong g. Cell Rep. 2019 Dec 3;29(10):2936-2943.e4. doi: 10.1016/j.celrep.2019.10.112. Cell Rep. 2019. PMID: 31801061 Free article.
Recent development of AAV-based gene therapies for inner ear disorders.
Lan Y, Tao Y, Wang Y, Ke J, Yang Q, Liu X, Su B, Wu Y, Lin CP, Zhong G. Lan Y, et al. Among authors: zhong g. Gene Ther. 2020 Aug;27(7-8):329-337. doi: 10.1038/s41434-020-0155-7. Epub 2020 May 18. Gene Ther. 2020. PMID: 32424232 Free PMC article. Review.
2,534 results