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Computational design of mechanically coupled axle-rotor protein assemblies.
Courbet A, Hansen J, Hsia Y, Bethel N, Park YJ, Xu C, Moyer A, Boyken SE, Ueda G, Nattermann U, Nagarajan D, Silva DA, Sheffler W, Quispe J, Nord A, King N, Bradley P, Veesler D, Kollman J, Baker D. Courbet A, et al. Among authors: xu c. Science. 2022 Apr 22;376(6591):383-390. doi: 10.1126/science.abm1183. Epub 2022 Apr 21. Science. 2022. PMID: 35446645 Free PMC article.
High thermodynamic stability of parametrically designed helical bundles.
Huang PS, Oberdorfer G, Xu C, Pei XY, Nannenga BL, Rogers JM, DiMaio F, Gonen T, Luisi B, Baker D. Huang PS, et al. Among authors: xu c. Science. 2014 Oct 24;346(6208):481-485. doi: 10.1126/science.1257481. Science. 2014. PMID: 25342806 Free PMC article.
Design of a hyperstable 60-subunit protein dodecahedron. [corrected].
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Hsia Y, et al. Among authors: xu c. Nature. 2016 Jul 7;535(7610):136-9. doi: 10.1038/nature18010. Epub 2016 Jun 15. Nature. 2016. PMID: 27309817 Free PMC article.
Corrigendum: Design of a hyperstable 60-subunit protein icosahedron.
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Hsia Y, et al. Among authors: xu c. Nature. 2016 Dec 1;540(7631):150. doi: 10.1038/nature20108. Epub 2016 Oct 19. Nature. 2016. PMID: 27760110 No abstract available.
Computational design of transmembrane pores.
Xu C, Lu P, Gamal El-Din TM, Pei XY, Johnson MC, Uyeda A, Bick MJ, Xu Q, Jiang D, Bai H, Reggiano G, Hsia Y, Brunette TJ, Dou J, Ma D, Lynch EM, Boyken SE, Huang PS, Stewart L, DiMaio F, Kollman JM, Luisi BF, Matsuura T, Catterall WA, Baker D. Xu C, et al. Among authors: xu q. Nature. 2020 Sep;585(7823):129-134. doi: 10.1038/s41586-020-2646-5. Epub 2020 Aug 26. Nature. 2020. PMID: 32848250 Free PMC article.
F-domain valency determines outcome of signaling through the angiopoietin pathway.
Zhao YT, Fallas JA, Saini S, Ueda G, Somasundaram L, Zhou Z, Xavier Raj I, Xu C, Carter L, Wrenn S, Mathieu J, Sellers DL, Baker D, Ruohola-Baker H. Zhao YT, et al. Among authors: xu c. EMBO Rep. 2021 Dec 6;22(12):e53471. doi: 10.15252/embr.202153471. Epub 2021 Oct 26. EMBO Rep. 2021. PMID: 34698433 Free PMC article.
De novo design of obligate ABC-type heterotrimeric proteins.
Bermeo S, Favor A, Chang YT, Norris A, Boyken SE, Hsia Y, Haddox HK, Xu C, Brunette TJ, Wysocki VH, Bhabha G, Ekiert DC, Baker D. Bermeo S, et al. Among authors: xu c. Nat Struct Mol Biol. 2022 Dec;29(12):1266-1276. doi: 10.1038/s41594-022-00879-4. Epub 2022 Dec 15. Nat Struct Mol Biol. 2022. PMID: 36522429 Free PMC article.
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