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Prolonged viral suppression with anti-HIV-1 antibody therapy.
Gaebler C, Nogueira L, Stoffel E, Oliveira TY, Breton G, Millard KG, Turroja M, Butler A, Ramos V, Seaman MS, Reeves JD, Petroupoulos CJ, Shimeliovich I, Gazumyan A, Jiang CS, Jilg N, Scheid JF, Gandhi R, Walker BD, Sneller MC, Fauci A, Chun TW, Caskey M, Nussenzweig MC. Gaebler C, et al. Among authors: fauci a. Nature. 2022 Jun;606(7913):368-374. doi: 10.1038/s41586-022-04597-1. Epub 2022 Apr 13. Nature. 2022. PMID: 35418681 Free PMC article.
Early antibody therapy can induce long-lasting immunity to SHIV.
Nishimura Y, Gautam R, Chun TW, Sadjadpour R, Foulds KE, Shingai M, Klein F, Gazumyan A, Golijanin J, Donaldson M, Donau OK, Plishka RJ, Buckler-White A, Seaman MS, Lifson JD, Koup RA, Fauci AS, Nussenzweig MC, Martin MA. Nishimura Y, et al. Among authors: fauci as. Nature. 2017 Mar 23;543(7646):559-563. doi: 10.1038/nature21435. Epub 2017 Mar 13. Nature. 2017. PMID: 28289286 Free PMC article.
Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy.
Blazkova J, Gao F, Marichannegowda MH, Justement JS, Shi V, Whitehead EJ, Schneck RF, Huiting ED, Gittens K, Cottrell M, Benko E, Kovacs C, Lack J, Sneller MC, Moir S, Fauci AS, Chun TW. Blazkova J, et al. Nat Med. 2021 Nov;27(11):1893-1898. doi: 10.1038/s41591-021-01503-6. Epub 2021 Oct 28. Nat Med. 2021. PMID: 34711975 Clinical Trial.
Combination anti-HIV antibodies provide sustained virological suppression.
Sneller MC, Blazkova J, Justement JS, Shi V, Kennedy BD, Gittens K, Tolstenko J, McCormack G, Whitehead EJ, Schneck RF, Proschan MA, Benko E, Kovacs C, Oguz C, Seaman MS, Caskey M, Nussenzweig MC, Fauci AS, Moir S, Chun TW. Sneller MC, et al. Among authors: fauci as. Nature. 2022 Jun;606(7913):375-381. doi: 10.1038/s41586-022-04797-9. Epub 2022 Jun 1. Nature. 2022. PMID: 35650437 Free PMC article. Clinical Trial.
Re-emergence of HIV after stopping therapy.
Chun TW, Davey RT Jr, Engel D, Lane HC, Fauci AS. Chun TW, et al. Among authors: fauci as. Nature. 1999 Oct 28;401(6756):874-5. doi: 10.1038/44755. Nature. 1999. PMID: 10553903 No abstract available.
1,146 results