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Chaotropic Effects in Sub/Supercritical Fluid Chromatography via Ammonium Hydroxide in Water-Rich Modifiers: Enabling Separation of Peptides and Highly Polar Pharmaceuticals at the Preparative Scale.
Liu J, Makarov AA, Bennett R, Haidar Ahmad IA, DaSilva J, Reibarkh M, Mangion I, Mann BF, Regalado EL. Liu J, et al. Among authors: mann bf. Anal Chem. 2019 Nov 5;91(21):13907-13915. doi: 10.1021/acs.analchem.9b03408. Epub 2019 Oct 8. Anal Chem. 2019. PMID: 31549812
In silico method development for the reversed-phase liquid chromatography separation of proteins using chaotropic mobile phase modifiers.
Haidar Ahmad IA, Bennett R, Makey D, Shchurik V, Lhotka H, Mann BF, McClain R, Lu T, Hua X, Strulson CA, Loughney JW, Mangion I, Makarov AA, Regalado EL. Haidar Ahmad IA, et al. Among authors: mann bf. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Feb 24;1173:122587. doi: 10.1016/j.jchromb.2021.122587. Online ahead of print. J Chromatogr B Analyt Technol Biomed Life Sci. 2021. PMID: 33845343
Design of an in vitro biocatalytic cascade for the manufacture of islatravir.
Huffman MA, Fryszkowska A, Alvizo O, Borra-Garske M, Campos KR, Canada KA, Devine PN, Duan D, Forstater JH, Grosser ST, Halsey HM, Hughes GJ, Jo J, Joyce LA, Kolev JN, Liang J, Maloney KM, Mann BF, Marshall NM, McLaughlin M, Moore JC, Murphy GS, Nawrat CC, Nazor J, Novick S, Patel NR, Rodriguez-Granillo A, Robaire SA, Sherer EC, Truppo MD, Whittaker AM, Verma D, Xiao L, Xu Y, Yang H. Huffman MA, et al. Among authors: mann bf. Science. 2019 Dec 6;366(6470):1255-1259. doi: 10.1126/science.aay8484. Science. 2019. PMID: 31806816
A kinase-cGAS cascade to synthesize a therapeutic STING activator.
McIntosh JA, Liu Z, Andresen BM, Marzijarani NS, Moore JC, Marshall NM, Borra-Garske M, Obligacion JV, Fier PS, Peng F, Forstater JH, Winston MS, An C, Chang W, Lim J, Huffman MA, Miller SP, Tsay FR, Altman MD, Lesburg CA, Steinhuebel D, Trotter BW, Cumming JN, Northrup A, Bu X, Mann BF, Biba M, Hiraga K, Murphy GS, Kolev JN, Makarewicz A, Pan W, Farasat I, Bade RS, Stone K, Duan D, Alvizo O, Adpressa D, Guetschow E, Hoyt E, Regalado EL, Castro S, Rivera N, Smith JP, Wang F, Crespo A, Verma D, Axnanda S, Dance ZEX, Devine PN, Tschaen D, Canada KA, Bulger PG, Sherry BD, Truppo MD, Ruck RT, Campeau LC, Bennett DJ, Humphrey GR, Campos KR, Maddess ML. McIntosh JA, et al. Among authors: mann bf. Nature. 2022 Mar;603(7901):439-444. doi: 10.1038/s41586-022-04422-9. Epub 2022 Mar 16. Nature. 2022. PMID: 35296845
43 results