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Page 1
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis.
Mentrup T, Stumpff-Niggemann AY, Leinung N, Schlosser C, Schubert K, Wehner R, Tunger A, Schatz V, Neubert P, Gradtke AC, Wolf J, Rose-John S, Saftig P, Dalpke A, Jantsch J, Schmitz M, Fluhrer R, Jacobsen ID, Schröder B. Mentrup T, et al. Nat Commun. 2022 Apr 6;13(1):1880. doi: 10.1038/s41467-022-29474-3. Nat Commun. 2022. PMID: 35388002 Free PMC article.
The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
Niemeyer J, Mentrup T, Heidasch R, Müller SA, Biswas U, Meyer R, Papadopoulou AA, Dederer V, Haug-Kröper M, Adamski V, Lüllmann-Rauch R, Bergmann M, Mayerhofer A, Saftig P, Wennemuth G, Jessberger R, Fluhrer R, Lichtenthaler SF, Lemberg MK, Schröder B. Niemeyer J, et al. Among authors: mentrup t. EMBO Rep. 2019 Mar;20(3):e46449. doi: 10.15252/embr.201846449. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733280 Free PMC article.
Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Papadopoulou AA, Müller SA, Mentrup T, Shmueli MD, Niemeyer J, Haug-Kröper M, von Blume J, Mayerhofer A, Feederle R, Schröder B, Lichtenthaler SF, Fluhrer R. Papadopoulou AA, et al. Among authors: mentrup t. EMBO Rep. 2019 Mar;20(3):e46451. doi: 10.15252/embr.201846451. Epub 2019 Feb 7. EMBO Rep. 2019. PMID: 30733281 Free PMC article.
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Mentrup T, Theodorou K, Cabrera-Cabrera F, Helbig AO, Happ K, Gijbels M, Gradtke AC, Rabe B, Fukumori A, Steiner H, Tholey A, Fluhrer R, Donners M, Schröder B. Mentrup T, et al. J Exp Med. 2019 Apr 1;216(4):807-830. doi: 10.1084/jem.20171438. Epub 2019 Feb 28. J Exp Med. 2019. PMID: 30819724 Free PMC article.
Intramembrane proteases protect from atherosclerosis.
Mentrup T, Schröder B. Mentrup T, et al. Aging (Albany NY). 2019 Oct 4;11(19):8041-8043. doi: 10.18632/aging.102342. Epub 2019 Oct 4. Aging (Albany NY). 2019. PMID: 31584876 Free PMC article. No abstract available.
27 results