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Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.
Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL. Kitamura H, et al. J Clin Invest. 2011 Jul;121(7):2863-75. doi: 10.1172/JCI45589. Epub 2011 Jun 6. J Clin Invest. 2011. PMID: 21646718 Free PMC article.
Interleukin-1beta induces increased transcriptional activation of the transforming growth factor-beta-activating integrin subunit beta8 through altering chromatin architecture.
Markovics JA, Araya J, Cambier S, Somanath S, Gline S, Jablons D, Hill A, Wolters PJ, Nishimura SL. Markovics JA, et al. Among authors: wolters pj. J Biol Chem. 2011 Oct 21;286(42):36864-74. doi: 10.1074/jbc.M111.276790. Epub 2011 Aug 30. J Biol Chem. 2011. PMID: 21878622 Free PMC article.
Selective targeting of TGF-β activation to treat fibroinflammatory airway disease.
Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. Minagawa S, et al. Sci Transl Med. 2014 Jun 18;6(241):241ra79. doi: 10.1126/scitranslmed.3008074. Sci Transl Med. 2014. PMID: 24944194 Free PMC article.
Age-dependent regulation of cell-mediated collagen turnover.
Podolsky MJ, Yang CD, Valenzuela CL, Datta R, Huang SK, Nishimura SL, Dallas SL, Wolters PJ, Le Saux CJ, Atabai K. Podolsky MJ, et al. Among authors: wolters pj. JCI Insight. 2020 May 21;5(10):e137519. doi: 10.1172/jci.insight.137519. JCI Insight. 2020. PMID: 32315288 Free PMC article.
227 results