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Page 1
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
Grabner GF, Guttenberger N, Mayer N, Migglautsch-Sulzer AK, Lembacher-Fadum C, Fawzy N, Bulfon D, Hofer P, Züllig T, Hartig L, Kulminskaya N, Chalhoub G, Schratter M, Radner FPW, Preiss-Landl K, Masser S, Lass A, Zechner R, Gruber K, Oberer M, Breinbauer R, Zimmermann R. Grabner GF, et al. Among authors: lembacher fadum c. J Am Chem Soc. 2022 Apr 13;144(14):6237-6250. doi: 10.1021/jacs.1c10836. Epub 2022 Apr 1. J Am Chem Soc. 2022. PMID: 35362954 Free PMC article.
Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline.
Dornisch E, Pletz J, Glabonjat RA, Martin F, Lembacher-Fadum C, Neger M, Högenauer C, Francesconi K, Kroutil W, Zangger K, Breinbauer R, Zechner EL. Dornisch E, et al. Among authors: lembacher fadum c. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14753-14757. doi: 10.1002/anie.201707737. Epub 2017 Oct 18. Angew Chem Int Ed Engl. 2017. PMID: 28977734 Free PMC article.
Simultaneous quantification of enterotoxins tilimycin and tilivalline in biological matrices using HPLC high resolution ESMS2 based on isotopically 15N-labeled internal standards.
Glabonjat RA, Kitsera M, Unterhauser K, Lembacher-Fadum C, Högenauer C, Raber G, Breinbauer R, Zechner EL. Glabonjat RA, et al. Among authors: lembacher fadum c. Talanta. 2021 Jan 15;222:121677. doi: 10.1016/j.talanta.2020.121677. Epub 2020 Sep 17. Talanta. 2021. PMID: 33167283 Free article.
Enterotoxin tilimycin from gut-resident Klebsiella promotes mutational evolution and antibiotic resistance in mice.
Kienesberger S, Cosic A, Kitsera M, Raffl S, Hiesinger M, Leitner E, Halwachs B, Gorkiewicz G, Glabonjat RA, Raber G, Lembacher-Fadum C, Breinbauer R, Schild S, Zechner EL. Kienesberger S, et al. Among authors: lembacher fadum c. Nat Microbiol. 2022 Nov;7(11):1834-1848. doi: 10.1038/s41564-022-01260-3. Epub 2022 Oct 26. Nat Microbiol. 2022. PMID: 36289400 Free PMC article.
Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities.
Unterhauser K, Pöltl L, Schneditz G, Kienesberger S, Glabonjat RA, Kitsera M, Pletz J, Josa-Prado F, Dornisch E, Lembacher-Fadum C, Roier S, Gorkiewicz G, Lucena D, Barasoain I, Kroutil W, Wiedner M, Loizou JI, Breinbauer R, Díaz JF, Schild S, Högenauer C, Zechner EL. Unterhauser K, et al. Among authors: lembacher fadum c. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3774-3783. doi: 10.1073/pnas.1819154116. Epub 2019 Feb 11. Proc Natl Acad Sci U S A. 2019. PMID: 30808763 Free PMC article.
Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations.
Pöltl L, Kitsera M, Raffl S, Schild S, Cosic A, Kienesberger S, Unterhauser K, Raber G, Lembacher-Fadum C, Breinbauer R, Gorkiewicz G, Sebastian C, Hoefler G, Zechner EL. Pöltl L, et al. Among authors: lembacher fadum c. Cell Rep. 2023 Mar 28;42(3):112199. doi: 10.1016/j.celrep.2023.112199. Epub 2023 Mar 3. Cell Rep. 2023. PMID: 36870054 Free article.