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Page 1
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lövestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW. Schweighauser M, et al. Among authors: murzin ag. Nature. 2022 May;605(7909):310-314. doi: 10.1038/s41586-022-04650-z. Epub 2022 Mar 28. Nature. 2022. PMID: 35344985 Free PMC article.
Cryo-EM structures of tau filaments from Alzheimer's disease.
Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Fitzpatrick AWP, et al. Among authors: murzin ag. Nature. 2017 Jul 13;547(7662):185-190. doi: 10.1038/nature23002. Epub 2017 Jul 5. Nature. 2017. PMID: 28678775 Free PMC article.
Structures of filaments from Pick's disease reveal a novel tau protein fold.
Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Falcon B, et al. Among authors: murzin ag. Nature. 2018 Sep;561(7721):137-140. doi: 10.1038/s41586-018-0454-y. Epub 2018 Aug 29. Nature. 2018. PMID: 30158706 Free PMC article.
Novel tau filament fold in corticobasal degeneration.
Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Zhang W, et al. Among authors: murzin ag. Nature. 2020 Apr;580(7802):283-287. doi: 10.1038/s41586-020-2043-0. Epub 2020 Feb 12. Nature. 2020. PMID: 32050258 Free PMC article.
Structures of α-synuclein filaments from multiple system atrophy.
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Schweighauser M, et al. Among authors: murzin ag. Nature. 2020 Sep;585(7825):464-469. doi: 10.1038/s41586-020-2317-6. Epub 2020 May 27. Nature. 2020. PMID: 32461689 Free PMC article.
Structure-based classification of tauopathies.
Shi Y, Zhang W, Yang Y, Murzin AG, Falcon B, Kotecha A, van Beers M, Tarutani A, Kametani F, Garringer HJ, Vidal R, Hallinan GI, Lashley T, Saito Y, Murayama S, Yoshida M, Tanaka H, Kakita A, Ikeuchi T, Robinson AC, Mann DMA, Kovacs GG, Revesz T, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Shi Y, et al. Among authors: murzin ag. Nature. 2021 Oct;598(7880):359-363. doi: 10.1038/s41586-021-03911-7. Epub 2021 Sep 29. Nature. 2021. PMID: 34588692 Free PMC article.
Structure of pathological TDP-43 filaments from ALS with FTLD.
Arseni D, Hasegawa M, Murzin AG, Kametani F, Arai M, Yoshida M, Ryskeldi-Falcon B. Arseni D, et al. Among authors: murzin ag. Nature. 2022 Jan;601(7891):139-143. doi: 10.1038/s41586-021-04199-3. Epub 2021 Dec 8. Nature. 2022. PMID: 34880495 Free PMC article.
Cryo-EM structures of amyloid-β 42 filaments from human brains.
Yang Y, Arseni D, Zhang W, Huang M, Lövestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M. Yang Y, et al. Among authors: murzin ag. Science. 2022 Jan 14;375(6577):167-172. doi: 10.1126/science.abm7285. Epub 2022 Jan 13. Science. 2022. PMID: 35025654 Free PMC article.
117 results