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Design of protein-binding proteins from the target structure alone.
Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Cao L, et al. Among authors: yang a, yang w. Nature. 2022 May;605(7910):551-560. doi: 10.1038/s41586-022-04654-9. Epub 2022 Mar 24. Nature. 2022. PMID: 35332283 Free PMC article.
De novo design of buttressed loops for sculpting protein functions.
Jiang H, Jude KM, Wu K, Fallas J, Ueda G, Brunette TJ, Hicks DR, Pyles H, Yang A, Carter L, Lamb M, Li X, Levine PM, Stewart L, Garcia KC, Baker D. Jiang H, et al. Among authors: yang a. Nat Chem Biol. 2024 Aug;20(8):974-980. doi: 10.1038/s41589-024-01632-2. Epub 2024 May 30. Nat Chem Biol. 2024. PMID: 38816644 Free PMC article.
Expanding the genetic code of Mus musculus.
Han S, Yang A, Lee S, Lee HW, Park CB, Park HS. Han S, et al. Among authors: yang a. Nat Commun. 2017 Feb 21;8:14568. doi: 10.1038/ncomms14568. Nat Commun. 2017. PMID: 28220771 Free PMC article.
Akt Kinase-Mediated Checkpoint of cGAS DNA Sensing Pathway.
Seo GJ, Yang A, Tan B, Kim S, Liang Q, Choi Y, Yuan W, Feng P, Park HS, Jung JU. Seo GJ, et al. Among authors: yang a. Cell Rep. 2015 Oct 13;13(2):440-9. doi: 10.1016/j.celrep.2015.09.007. Epub 2015 Oct 1. Cell Rep. 2015. PMID: 26440888 Free PMC article.
5,528 results