Lee JM - Search Results

1

Genetic modifiers of Huntington disease differentially influence motor and cognitive domains.

Lee JM, Huang Y, Orth M, Gillis T, Siciliano J, Hong E, Mysore JS, Lucente D, Wheeler VC, Seong IS, McLean ZL, Mills JA, McAllister B, Lobanov SV, Massey TH, Ciosi M, Landwehrmeyer GB, Paulsen JS, Dorsey ER, Shoulson I, Sampaio C, Monckton DG, Kwak S, Holmans P, Jones L, MacDonald ME, Long JD, Gusella JF. Lee JM, et al. Am J Hum Genet. 2022 May 5;109(5):885-899. doi: 10.1016/j.ajhg.2022.03.004. Epub 2022 Mar 23. Am J Hum Genet. 2022. PMID: 35325614 Free PMC article.

2

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism.

Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, MacDonald ME. Seong IS, et al. Among authors: lee jm. Hum Mol Genet. 2005 Oct 1;14(19):2871-80. doi: 10.1093/hmg/ddi319. Epub 2005 Aug 22. Hum Mol Genet. 2005. PMID: 16115812

3

Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism.

Lee JM, Ivanova EV, Seong IS, Cashorali T, Kohane I, Gusella JF, MacDonald ME. Lee JM, et al. PLoS Genet. 2007 Aug;3(8):e135. doi: 10.1371/journal.pgen.0030135. Epub 2007 Jun 27. PLoS Genet. 2007. PMID: 17708681 Free PMC article.

4

Huntingtin facilitates polycomb repressive complex 2.

Seong IS, Woda JM, Song JJ, Lloret A, Abeyrathne PD, Woo CJ, Gregory G, Lee JM, Wheeler VC, Walz T, Kingston RE, Gusella JF, Conlon RA, MacDonald ME. Seong IS, et al. Among authors: lee jm. Hum Mol Genet. 2010 Feb 15;19(4):573-83. doi: 10.1093/hmg/ddp524. Epub 2009 Nov 23. Hum Mol Genet. 2010. PMID: 19933700 Free PMC article.

5

A novel approach to investigate tissue-specific trinucleotide repeat instability.

Lee JM, Zhang J, Su AI, Walker JR, Wiltshire T, Kang K, Dragileva E, Gillis T, Lopez ET, Boily MJ, Cyr M, Kohane I, Gusella JF, MacDonald ME, Wheeler VC. Lee JM, et al. BMC Syst Biol. 2010 Mar 19;4:29. doi: 10.1186/1752-0509-4-29. BMC Syst Biol. 2010. PMID: 20302627 Free PMC article.

6

Distinct early molecular responses to mutations causing vLINCL and JNCL presage ATP synthase subunit C accumulation in cerebellar cells.

Cao Y, Staropoli JF, Biswas S, Espinola JA, MacDonald ME, Lee JM, Cotman SL. Cao Y, et al. Among authors: lee jm. PLoS One. 2011 Feb 17;6(2):e17118. doi: 10.1371/journal.pone.0017118. PLoS One. 2011. PMID: 21359198 Free PMC article.

7

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.

Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, MacDonald ME, Seong IS. Reis SA, et al. Among authors: lee jm. Hum Mol Genet. 2011 Jun 15;20(12):2344-55. doi: 10.1093/hmg/ddr127. Epub 2011 Mar 29. Hum Mol Genet. 2011. PMID: 21447599 Free PMC article.

8

HD CAG-correlated gene expression changes support a simple dominant gain of function.

Jacobsen JC, Gregory GC, Woda JM, Thompson MN, Coser KR, Murthy V, Kohane IS, Gusella JF, Seong IS, MacDonald ME, Shioda T, Lee JM. Jacobsen JC, et al. Among authors: lee jm. Hum Mol Genet. 2011 Jul 15;20(14):2846-60. doi: 10.1093/hmg/ddr195. Epub 2011 May 2. Hum Mol Genet. 2011. PMID: 21536587 Free PMC article.

9

Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative.

Fossale E, Seong IS, Coser KR, Shioda T, Kohane IS, Wheeler VC, Gusella JF, MacDonald ME, Lee JM. Fossale E, et al. Among authors: lee jm. Hum Mol Genet. 2011 Nov 1;20(21):4258-67. doi: 10.1093/hmg/ddr355. Epub 2011 Aug 12. Hum Mol Genet. 2011. PMID: 21840924 Free PMC article.

10

Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.

Lee JM, Pinto RM, Gillis T, St Claire JC, Wheeler VC. Lee JM, et al. PLoS One. 2011;6(8):e23647. doi: 10.1371/journal.pone.0023647. Epub 2011 Aug 29. PLoS One. 2011. PMID: 21897851 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

7,134 results

Search Page

Filters