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Activation of GPR75 Signaling Pathway Contributes to the Effect of a 20-HETE Mimetic, 5,14-HEDGE, to Prevent Hypotensive and Tachycardic Responses to Lipopolysaccharide in a Rat Model of Septic Shock.
Tunctan B, Senol SP, Temiz-Resitoglu M, Yilmaz DE, Guden DS, Bahceli O, Horat MF, Sahan-Firat S, Sari AN, Falck JR, Anugu RR, Malik KU. Tunctan B, et al. Among authors: horat mf. J Cardiovasc Pharmacol. 2022 Aug 1;80(2):276-293. doi: 10.1097/FJC.0000000000001265. J Cardiovasc Pharmacol. 2022. PMID: 35323151
Pharmacological inhibition of soluble epoxide hydrolase attenuates chronic experimental autoimmune encephalomyelitis by modulating inflammatory and anti-inflammatory pathways in an inflammasome-dependent and -independent manner.
Biliktu M, Senol SP, Temiz-Resitoglu M, Guden DS, Horat MF, Sahan-Firat S, Sevim S, Tunctan B. Biliktu M, et al. Among authors: horat mf. Inflammopharmacology. 2020 Dec;28(6):1509-1524. doi: 10.1007/s10787-020-00691-w. Epub 2020 Mar 3. Inflammopharmacology. 2020. PMID: 32128702
Pro-inflammatory GPR75 and anti-apoptotic phospholipase signaling pathways contribute to the ameliorating effect of soluble epoxide hydrolase inhibition on chronic experimental autoimmune encephalomyelitis in mice.
Horat MF, Senol SP, Bahceli O, Temiz-Resitoglu M, Sahan-Firat S, Sevim S, Tunctan B. Horat MF, et al. Cell Mol Biol (Noisy-le-grand). 2023 Oct 31;69(10):9-16. doi: 10.14715/cmb/2023.69.10.2. Cell Mol Biol (Noisy-le-grand). 2023. PMID: 37953590