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Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation.
Mead BE, Hattori K, Levy L, Imada S, Goto N, Vukovic M, Sze D, Kummerlowe C, Matute JD, Duan J, Langer R, Blumberg RS, Ordovas-Montanes J, Yilmaz ÖH, Karp JM, Shalek AK. Mead BE, et al. Among authors: goto n. Nat Biomed Eng. 2022 Apr;6(4):476-494. doi: 10.1038/s41551-022-00863-9. Epub 2022 Mar 21. Nat Biomed Eng. 2022. PMID: 35314801 Free PMC article.
Arid1a is essential for intestinal stem cells through Sox9 regulation.
Hiramatsu Y, Fukuda A, Ogawa S, Goto N, Ikuta K, Tsuda M, Matsumoto Y, Kimura Y, Yoshioka T, Takada Y, Maruno T, Hanyu Y, Tsuruyama T, Wang Z, Akiyama H, Takaishi S, Miyoshi H, Taketo MM, Chiba T, Seno H. Hiramatsu Y, et al. Among authors: goto n. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1704-1713. doi: 10.1073/pnas.1804858116. Epub 2019 Jan 11. Proc Natl Acad Sci U S A. 2019. PMID: 30635419 Free PMC article.
Gene expression profile of Dclk1+ cells in intestinal tumors.
Yamaga Y, Fukuda A, Nakanishi Y, Goto N, Matsumoto Y, Yoshioka T, Maruno T, Chiba T, Seno H. Yamaga Y, et al. Among authors: goto n. Dig Liver Dis. 2018 Dec;50(12):1353-1361. doi: 10.1016/j.dld.2018.06.011. Epub 2018 Jun 22. Dig Liver Dis. 2018. PMID: 30001952
Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.
Kakiuchi N, Yoshida K, Uchino M, Kihara T, Akaki K, Inoue Y, Kawada K, Nagayama S, Yokoyama A, Yamamoto S, Matsuura M, Horimatsu T, Hirano T, Goto N, Takeuchi Y, Ochi Y, Shiozawa Y, Kogure Y, Watatani Y, Fujii Y, Kim SK, Kon A, Kataoka K, Yoshizato T, Nakagawa MM, Yoda A, Nanya Y, Makishima H, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Sugihara E, Sato TA, Maruyama T, Miyoshi H, Taketo MM, Oishi J, Inagaki R, Ueda Y, Okamoto S, Okajima H, Sakai Y, Sakurai T, Haga H, Hirota S, Ikeuchi H, Nakase H, Marusawa H, Chiba T, Takeuchi O, Miyano S, Seno H, Ogawa S. Kakiuchi N, et al. Among authors: goto n. Nature. 2020 Jan;577(7789):260-265. doi: 10.1038/s41586-019-1856-1. Epub 2019 Dec 18. Nature. 2020. PMID: 31853061 Free article.
Brg1 is required to maintain colorectal cancer stem cells.
Yoshikawa T, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H. Yoshikawa T, et al. Among authors: goto n. J Pathol. 2021 Nov;255(3):257-269. doi: 10.1002/path.5759. Epub 2021 Aug 20. J Pathol. 2021. PMID: 34415580
JNK pathway plays a critical role for expansion of human colorectal cancer in the context of BRG1 suppression.
Yoshikawa T, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H. Yoshikawa T, et al. Among authors: goto n. Cancer Sci. 2022 Oct;113(10):3417-3427. doi: 10.1111/cas.15520. Epub 2022 Aug 17. Cancer Sci. 2022. PMID: 35924439 Free PMC article.
1,041 results