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Allosteric binders of ACE2 are promising anti-SARS-CoV-2 agents.
Hochuli JE, Jain S, Melo-Filho C, Sessions ZL, Bobrowski T, Choe J, Zheng J, Eastman R, Talley DC, Rai G, Simeonov A, Tropsha A, Muratov EN, Baljinnyam B, Zakharov AV. Hochuli JE, et al. Among authors: eastman r. bioRxiv [Preprint]. 2022 Mar 16:2022.03.15.484484. doi: 10.1101/2022.03.15.484484. bioRxiv. 2022. Update in: ACS Pharmacol Transl Sci. 2022 Jun 22;5(7):468-478. doi: 10.1021/acsptsci.2c00049 PMID: 35313579 Free PMC article. Updated. Preprint.
Small Molecule Antiviral Compound Collection (SMACC): a database to support the discovery of broad-spectrum antiviral drug molecules.
Martin HJ, Melo-Filho CC, Korn D, Eastman RT, Rai G, Simeonov A, Zakharov AV, Muratov E, Tropsha A. Martin HJ, et al. bioRxiv [Preprint]. 2022 Jul 11:2022.07.09.499397. doi: 10.1101/2022.07.09.499397. bioRxiv. 2022. Update in: Antiviral Res. 2023 Sep;217:105620. doi: 10.1016/j.antiviral.2023.105620 PMID: 35860225 Free PMC article. Updated. Preprint.
Pyrimidine Azepine Targets the Plasmodium bc 1 Complex and Displays Multistage Antimalarial Activity.
Calit J, Prajapati SK, Benavente ED, Araújo JE, Deng B, Miura K, Annunciato Y, Moura IMR, Usui M, Medeiros JF, Andrade CH, Silva-Mendonça S, Simeonov A, Eastman RT, Long CA, da Silva Araujo M, Williamson KC, Aguiar ACC, Bargieri DY. Calit J, et al. Among authors: eastman rt. JACS Au. 2024 Oct 7;4(10):3942-3952. doi: 10.1021/jacsau.4c00674. eCollection 2024 Oct 28. JACS Au. 2024. PMID: 39483245 Free PMC article.
Establishment of human post-vaccination SARS-CoV-2 standard reference sera.
Xiang J, Katz L, Winokur PL, Chaudhary A, Digmann B, Bradford R, Rashid S, Ghosh S, Robertson A, Menetski J, Xu M, Gao P, Chen CZ, Lee T, Poelaert B, Eastman RT, Hall MD, Stapleton JT. Xiang J, et al. Among authors: eastman rt. J Immunol Methods. 2024 Jul;530:113698. doi: 10.1016/j.jim.2024.113698. Epub 2024 May 31. J Immunol Methods. 2024. PMID: 38823574 Free article.
Identification of Potent, Broad-Spectrum Coronavirus Main Protease Inhibitors for Pandemic Preparedness.
Barkan DT, Garland K, Zhang L, Eastman RT, Hesse M, Knapp M, Ornelas E, Tang J, Cortopassi WA, Wang Y, King F, Jia W, Nguyen Z, Frank AO, Chan R, Fang E, Fuller D, Busby S, Carias H, Donahue K, Tandeske L, Diagana TT, Jarrousse N, Moser H, Sarko C, Dovala D, Moquin S, Marx VM. Barkan DT, et al. Among authors: eastman rt. J Med Chem. 2024 Oct 10;67(19):17454-17471. doi: 10.1021/acs.jmedchem.4c01404. Epub 2024 Sep 27. J Med Chem. 2024. PMID: 39332817 Free PMC article.
Prevalence of Distal Symmetrical Polyneuropathy by Diabetes Prevention Program Treatment Group, Diabetes Status, Duration of Diabetes, and Cumulative Glycemic Exposure.
Lee CG, Ciarleglio A, Edelstein SL, Crandall JP, Dabelea D, Goldberg RB, Kahn SE, Knowler WC, Ma MT, White NH, Herman WH; Diabetes Prevention Program Research Group. Lee CG, et al. Diabetes Care. 2024 May 1;47(5):810-817. doi: 10.2337/dc23-2009. Diabetes Care. 2024. PMID: 38502874 Clinical Trial.
Implementation of eLearning solutions for patients with chronic pain conditions.
Philpot LM, Ahrens DJ, Eastman RJ, Mohabbat AB, Mosman EA, Ramar P, Reinschmidt KJ, Roellinger DL, Ebbert JO. Philpot LM, et al. Among authors: eastman rj. Digit Health. 2023 Nov 27;9:20552076231216404. doi: 10.1177/20552076231216404. eCollection 2023 Jan-Dec. Digit Health. 2023. PMID: 38033514 Free PMC article.
228 results