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Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.
Nguyen-Tu MS, Harris J, Martinez-Sanchez A, Chabosseau P, Hu M, Georgiadou E, Pollard A, Otero P, Lopez-Noriega L, Leclerc I, Sakamoto K, Schmoll D, Smith DM, Carling D, Rutter GA. Nguyen-Tu MS, et al. Diabetologia. 2022 Jun;65(6):997-1011. doi: 10.1007/s00125-022-05673-x. Epub 2022 Mar 16. Diabetologia. 2022. PMID: 35294578 Free PMC article.
MiR-184 expression is regulated by AMPK in pancreatic islets.
Martinez-Sanchez A, Nguyen-Tu MS, Cebola I, Yavari A, Marchetti P, Piemonti L, de Koning E, Shapiro AMJ, Johnson P, Sakamoto K, Smith DM, Leclerc I, Ashrafian H, Ferrer J, Rutter GA. Martinez-Sanchez A, et al. FASEB J. 2018 May;32(5):2587-2600. doi: 10.1096/fj.201701100R. Epub 2018 Jan 8. FASEB J. 2018. PMID: 29269398 Free PMC article.
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function.
Cheung R, Pizza G, Chabosseau P, Rolando D, Tomas A, Burgoyne T, Wu Z, Salowka A, Thapa A, Macklin A, Cao Y, Nguyen-Tu MS, Dickerson MT, Jacobson DA, Marchetti P, Shapiro J, Piemonti L, de Koning E, Leclerc I, Bouzakri K, Sakamoto K, Smith DM, Rutter GA, Martinez-Sanchez A. Cheung R, et al. Among authors: nguyen tu ms. Diabetes. 2022 Jul 1;71(7):1525-1545. doi: 10.2337/db21-0803. Diabetes. 2022. PMID: 35476777 Free PMC article.
LKB1 and AMPK differentially regulate pancreatic β-cell identity.
Kone M, Pullen TJ, Sun G, Ibberson M, Martinez-Sanchez A, Sayers S, Nguyen-Tu MS, Kantor C, Swisa A, Dor Y, Gorman T, Ferrer J, Thorens B, Reimann F, Gribble F, McGinty JA, Chen L, French PM, Birzele F, Hildebrandt T, Uphues I, Rutter GA. Kone M, et al. FASEB J. 2014 Nov;28(11):4972-85. doi: 10.1096/fj.14-257667. Epub 2014 Jul 28. FASEB J. 2014. PMID: 25070369 Free PMC article.
Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.
Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martínez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Tóth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H. Yavari A, et al. Cell Metab. 2016 May 10;23(5):821-36. doi: 10.1016/j.cmet.2016.04.003. Epub 2016 Apr 28. Cell Metab. 2016. PMID: 27133129 Free PMC article.
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