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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry.
Ferhati X, Jiménez-Moreno E, Hoyt EA, Salluce G, Cabeza-Cabrerizo M, Navo CD, Compañón I, Akkapeddi P, Matos MJ, Salaverri N, Garrido P, Martínez A, Laserna V, Murray TV, Jiménez-Osés G, Ravn P, Bernardes GJL, Corzana F. Ferhati X, et al. Among authors: navo cd. J Am Chem Soc. 2022 Mar 30;144(12):5284-5294. doi: 10.1021/jacs.1c07675. Epub 2022 Mar 16. J Am Chem Soc. 2022. PMID: 35293206 Free PMC article.
Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody.
Fernández EM, Navo CD, Martínez-Sáez N, Gonçalves-Pereira R, Somovilla VJ, Avenoza A, Busto JH, Bernardes GJ, Jiménez-Osés G, Corzana F, Fernández JM, Mellet CO, Peregrina JM. Fernández EM, et al. Among authors: navo cd. Org Lett. 2016 Aug 5;18(15):3890-3. doi: 10.1021/acs.orglett.6b01899. Epub 2016 Jul 25. Org Lett. 2016. PMID: 27453399
Cell-Penetrating Peptides Containing Fluorescent d-Cysteines.
Navo CD, Asín A, Gómez-Orte E, Gutiérrez-Jiménez MI, Compañón I, Ezcurra B, Avenoza A, Busto JH, Corzana F, Zurbano MM, Jiménez-Osés G, Cabello J, Peregrina JM. Navo CD, et al. Chemistry. 2018 Jun 4;24(31):7991-8000. doi: 10.1002/chem.201800603. Epub 2018 May 8. Chemistry. 2018. PMID: 29603441
Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
An L, Cogan DP, Navo CD, Jiménez-Osés G, Nair SK, van der Donk WA. An L, et al. Among authors: navo cd. Nat Chem Biol. 2018 Oct;14(10):928-933. doi: 10.1038/s41589-018-0122-4. Epub 2018 Sep 3. Nat Chem Biol. 2018. PMID: 30177849 Free PMC article.
Elusive Dehydroalanine Derivatives with Enhanced Reactivity.
Aydillo C, Mazo N, Navo CD, Jiménez-Osés G. Aydillo C, et al. Among authors: navo cd. Chembiochem. 2019 May 15;20(10):1246-1250. doi: 10.1002/cbic.201800758. Epub 2019 Apr 1. Chembiochem. 2019. PMID: 30650254
43 results