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Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.
Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E. Glatigny S, et al. Among authors: bettelli e. J Immunol. 2019 Mar 1;202(5):1373-1382. doi: 10.4049/jimmunol.1801425. Epub 2019 Jan 25. J Immunol. 2019. PMID: 30683697 Free PMC article. Clinical Trial.
S1P1 deletion differentially affects TH17 and Regulatory T cells.
Eken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M. Eken A, et al. Among authors: bettelli e. Sci Rep. 2017 Oct 10;7(1):12905. doi: 10.1038/s41598-017-13376-2. Sci Rep. 2017. PMID: 29018225 Free PMC article.
75 results