Timmers C - Search Results

1

Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images.

Pécot T, Cuitiño MC, Johnson RH, Timmers C, Leone G. Pécot T, et al. Among authors: timmers c. PLoS Comput Biol. 2022 Mar 14;18(3):e1009949. doi: 10.1371/journal.pcbi.1009949. eCollection 2022 Mar. PLoS Comput Biol. 2022. PMID: 35286300 Free PMC article.

2

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation.

Cuitiño MC, Pécot T, Sun D, Kladney R, Okano-Uchida T, Shinde N, Saeed R, Perez-Castro AJ, Webb A, Liu T, Bae SI, Clijsters L, Selner N, Coppola V, Timmers C, Ostrowski MC, Pagano M, Leone G. Cuitiño MC, et al. Among authors: timmers c. Cell Rep. 2019 Jun 18;27(12):3547-3560.e5. doi: 10.1016/j.celrep.2019.05.004. Epub 2019 May 23. Cell Rep. 2019. PMID: 31130414 Free PMC article.

3

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.

Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G. Caserta E, et al. Among authors: timmers c. Genes Dev. 2015 Aug 15;29(16):1707-20. doi: 10.1101/gad.262568.115. Genes Dev. 2015. PMID: 26302789 Free PMC article.

4

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.

Maiti B, Li J, de Bruin A, Gordon F, Timmers C, Opavsky R, Patil K, Tuttle J, Cleghorn W, Leone G. Maiti B, et al. Among authors: timmers c. J Biol Chem. 2005 May 6;280(18):18211-20. doi: 10.1074/jbc.M501410200. Epub 2005 Feb 18. J Biol Chem. 2005. PMID: 15722552 Free article.

5

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.

Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G. Sharma N, et al. Among authors: timmers c. J Biol Chem. 2006 Nov 24;281(47):36124-31. doi: 10.1074/jbc.M604152200. Epub 2006 Sep 27. J Biol Chem. 2006. PMID: 17008321 Free article.

6

Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation.

de Bruin A, Maiti B, Jakoi L, Timmers C, Buerki R, Leone G. de Bruin A, et al. Among authors: timmers c. J Biol Chem. 2003 Oct 24;278(43):42041-9. doi: 10.1074/jbc.M308105200. Epub 2003 Jul 31. J Biol Chem. 2003. PMID: 12893818 Free article.

7

Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb.

Saavedra HI, Wu L, de Bruin A, Timmers C, Rosol TJ, Weinstein M, Robinson ML, Leone G. Saavedra HI, et al. Among authors: timmers c. Cell Growth Differ. 2002 May;13(5):215-25. Cell Growth Differ. 2002. PMID: 12065245

8

Inactivation of E2F3 results in centrosome amplification.

Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G. Saavedra HI, et al. Among authors: timmers c. Cancer Cell. 2003 Apr;3(4):333-46. doi: 10.1016/s1535-6108(03)00083-7. Cancer Cell. 2003. PMID: 12726860 Free PMC article.

9

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.

Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G. Timmers C, et al. Mol Cell Biol. 2007 Jan;27(1):65-78. doi: 10.1128/MCB.02147-05. Mol Cell Biol. 2007. PMID: 17167174 Free PMC article.

10

The E2F1-3 transcription factors are essential for cellular proliferation.

Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: timmers c. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808

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