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USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation.
Zheng Q, Song B, Li G, Cai F, Wu M, Zhao Y, Jiang L, Guo T, Shen M, Hou H, Zhou Y, Zhao Y, Di A, Zhang L, Zeng F, Zhang XF, Luo H, Zhang X, Zhang H, Zeng Z, Huang TY, Dong C, Qing H, Zhang Y, Zhang Q, Wang X, Wu Y, Xu H, Song W, Wang X. Zheng Q, et al. Among authors: guo t. J Clin Invest. 2022 Mar 1;132(5):e152170. doi: 10.1172/JCI152170. J Clin Invest. 2022. PMID: 35229730 Free PMC article.
The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability.
Zeng F, Ma X, Zhu L, Xu Q, Zeng Y, Gao Y, Li G, Guo T, Zhang H, Tang X, Wang Z, Ye Z, Zheng L, Zhang H, Zheng Q, Li K, Lu J, Qi X, Luo H, Zhang X, Wang Z, Zhou Y, Yao Y, Ke R, Zhou Y, Liu Y, Sun H, Huang T, Shao Z, Xu H, Wang X. Zeng F, et al. Among authors: guo t. PLoS Biol. 2019 Dec 16;17(12):e3000525. doi: 10.1371/journal.pbio.3000525. eCollection 2019 Dec. PLoS Biol. 2019. PMID: 31841517 Free PMC article.
Microglial apolipoprotein E particles contribute to neuronal senescence and synaptotoxicity.
Wang N, Cai L, Pei X, Lin Z, Huang L, Liang C, Wei M, Shao L, Guo T, Huang F, Luo H, Zheng H, Chen XF, Leng L, Zhang YW, Wang X, Zhang J, Guo K, Wang Z, Zhang H, Zhao Y, Xu H. Wang N, et al. Among authors: guo t, guo k. iScience. 2024 May 16;27(6):110006. doi: 10.1016/j.isci.2024.110006. eCollection 2024 Jun 21. iScience. 2024. PMID: 38868202 Free PMC article.
6,003 results