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Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes.
Fasolino M, Schwartz GW, Patil AR, Mongia A, Golson ML, Wang YJ, Morgan A, Liu C, Schug J, Liu J, Wu M, Traum D, Kondo A, May CL, Goldman N, Wang W, Feldman M, Moore JH, Japp AS, Betts MR; HPAP Consortium; Faryabi RB, Naji A, Kaestner KH, Vahedi G. Fasolino M, et al. Among authors: kaestner kh. Nat Metab. 2022 Feb;4(2):284-299. doi: 10.1038/s42255-022-00531-x. Epub 2022 Feb 28. Nat Metab. 2022. PMID: 35228745 Free PMC article.
Computational workflow and interactive analysis of single-cell expression profiling of islets generated by the Human Pancreas Analysis Program.
Patil AR, Schug J; HPAP Consortium; Naji A, Kaestner KH, Faryabi RB, Vahedi G. Patil AR, et al. Among authors: kaestner kh. bioRxiv [Preprint]. 2023 Jan 3:2023.01.03.522578. doi: 10.1101/2023.01.03.522578. bioRxiv. 2023. Update in: Nat Metab. 2023 May;5(5):713-715. doi: 10.1038/s42255-023-00806-x PMID: 36711819 Free PMC article. Updated. Preprint.
Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset.
Golden GJ, Wu VH, Hamilton JT, Amses KR, Shapiro MR, Japp AS, Liu C, Pampena MB, Kuri-Cervantes L, Knox JJ, Gardner JS; HPAP Consortium; Atkinson MA, Brusko TM, Prak ETL, Kaestner KH, Naji A, Betts MR. Golden GJ, et al. Among authors: kaestner kh. bioRxiv [Preprint]. 2024 Sep 16:2024.04.23.590798. doi: 10.1101/2024.04.23.590798. bioRxiv. 2024. PMID: 39345402 Free PMC article. Preprint.
DNA Methylation-Based Assessment of Cell Composition in Human Pancreas and Islets.
Drawshy Z, Neiman D, Fridlich O, Peretz A, Magenheim J, Rozo AV, Doliba NM, Stoffers DA, Kaestner KH, Schatz DA, Wasserfall C, Campbell-Thompson M, Shapiro J, Kaplan T, Shemer R, Glaser B, Klochendler A, Dor Y. Drawshy Z, et al. Among authors: kaestner kh. Diabetes. 2024 Apr 1;73(4):554-564. doi: 10.2337/db23-0704. Diabetes. 2024. PMID: 38266068
TNFSF13 insufficiency disrupts human colonic epithelial cell-mediated B cell differentiation.
Ma X, Dawany N, Kondo A, Maurer K, Karakasheva T, Shraim R, Williams PA, Parham LR, Simon LA, Danan CH, Conrad MA, Piccoli DA, Devoto M, Sullivan KE, Kaestner KH, Kelsen JR, Hamilton KE. Ma X, et al. Among authors: kaestner kh. bioRxiv [Preprint]. 2024 Sep 23:2024.09.23.614260. doi: 10.1101/2024.09.23.614260. bioRxiv. 2024. PMID: 39386555 Free PMC article. Preprint.
3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility.
Trang KB, Sharma P, Cook L, Mount Z, Thomas RM, Kulkarni NN, Pahl MC, Pippin JA, Su C, Kaestner KH, O'Brien JM, Wagley Y, Hankenson KD, Jermusyk A, Hoskins JW, Amundadottir LT, Xu M, Brown KM, Anderson SA, Yang W, Titchenell PM, Seale P, Zemel BS, Chesi A, Romberg N, Levings MK, Grant SFA, Wells AD. Trang KB, et al. Among authors: kaestner kh. medRxiv [Preprint]. 2024 Aug 12:2024.08.12.24311676. doi: 10.1101/2024.08.12.24311676. medRxiv. 2024. PMID: 39185517 Free PMC article. Preprint.
416 results