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P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release.
Barberà-Cremades M, Baroja-Mazo A, Gomez AI, Machado F, Di Virgilio F, Pelegrín P. Barberà-Cremades M, et al. Among authors: pelegrin p. FASEB J. 2012 Jul;26(7):2951-62. doi: 10.1096/fj.12-205765. Epub 2012 Apr 6. FASEB J. 2012. PMID: 22490780
-Barbera-Cremades, M., Baroja-Mazo, A., Gomez, A. I., Machado, F., Di Virgilio, F., Pelegrin, P. P2X7 receptor-stimulation causes fever via PGE2 and IL-1beta release....
-Barbera-Cremades, M., Baroja-Mazo, A., Gomez, A. I., Machado, F., Di Virgilio, F., Pelegrin, P. P2X7 receptor-stimulation cau …
Cell volume regulation modulates NLRP3 inflammasome activation.
Compan V, Baroja-Mazo A, López-Castejón G, Gomez AI, Martínez CM, Angosto D, Montero MT, Herranz AS, Bazán E, Reimers D, Mulero V, Pelegrín P. Compan V, et al. Among authors: pelegrin p. Immunity. 2012 Sep 21;37(3):487-500. doi: 10.1016/j.immuni.2012.06.013. Epub 2012 Sep 13. Immunity. 2012. PMID: 22981536 Free article.
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P. Baroja-Mazo A, et al. Among authors: pelegrin p. Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952504
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.
Martín-Sánchez F, Diamond C, Zeitler M, Gomez AI, Baroja-Mazo A, Bagnall J, Spiller D, White M, Daniels MJ, Mortellaro A, Peñalver M, Paszek P, Steringer JP, Nickel W, Brough D, Pelegrín P. Martín-Sánchez F, et al. Among authors: pelegrin p. Cell Death Differ. 2016 Jul;23(7):1219-31. doi: 10.1038/cdd.2015.176. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868913 Free PMC article.
Involvement of the P2X7-NLRP3 axis in leukemic cell proliferation and death.
Salaro E, Rambaldi A, Falzoni S, Amoroso FS, Franceschini A, Sarti AC, Bonora M, Cavazzini F, Rigolin GM, Ciccone M, Audrito V, Deaglio S, Pelegrin P, Pinton P, Cuneo A, Di Virgilio F. Salaro E, et al. Among authors: pelegrin p. Sci Rep. 2016 May 25;6:26280. doi: 10.1038/srep26280. Sci Rep. 2016. PMID: 27221966 Free PMC article.
152 results