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Page 1
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.
Moltke I, Grarup N, Jørgensen ME, Bjerregaard P, Treebak JT, Fumagalli M, Korneliussen TS, Andersen MA, Nielsen TS, Krarup NT, Gjesing AP, Zierath JR, Linneberg A, Wu X, Sun G, Jin X, Al-Aama J, Wang J, Borch-Johnsen K, Pedersen O, Nielsen R, Albrechtsen A, Hansen T. Moltke I, et al. Among authors: nielsen ts, nielsen r. Nature. 2014 Aug 14;512(7513):190-3. doi: 10.1038/nature13425. Epub 2014 Jun 18. Nature. 2014. PMID: 25043022
Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain.
Jensen BA, Nielsen TS, Fritzen AM, Holm JB, Fjære E, Serup AK, Borkowski K, Risis S, Pærregaard SI, Søgaard I, Poupeau A, Poulsen M, Ma T, Sina C, Kiens B, Madsen L, Kristiansen K, Treebak JT. Jensen BA, et al. Among authors: nielsen ts. Metabolism. 2016 Dec;65(12):1706-1719. doi: 10.1016/j.metabol.2016.09.002. Epub 2016 Sep 12. Metabolism. 2016. PMID: 27832859 Free article.
Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity.
Shi H, Munk A, Nielsen TS, Daughtry MR, Larsson L, Li S, Høyer KF, Geisler HW, Sulek K, Kjøbsted R, Fisher T, Andersen MM, Shen Z, Hansen UK, England EM, Cheng Z, Højlund K, Wojtaszewski JFP, Yang X, Hulver MW, Helm RF, Treebak JT, Gerrard DE. Shi H, et al. Among authors: nielsen ts. Mol Metab. 2018 May;11:160-177. doi: 10.1016/j.molmet.2018.02.010. Epub 2018 Feb 24. Mol Metab. 2018. PMID: 29525407 Free PMC article.
Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise.
Brandão BB, Madsen S, Rabiee A, Oliverio M, Ruiz GP, Ferrucci DL, Branquinho JL, Razolli D, Pinto S, Nielsen TS, Festuccia WT, Martins AS, Guerra BA, Knittel TL, Søgaard D, Larsen S, Helge JW, Brandauer J, Velloso LA, Emanuelli B, Kornfeld JW, Kahn CR, Vienberg SG, Zierath JR, Treebak JT, Mori MA. Brandão BB, et al. Among authors: nielsen ts. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23932-23941. doi: 10.1073/pnas.2011243117. Epub 2020 Sep 8. Proc Natl Acad Sci U S A. 2020. PMID: 32900951 Free PMC article.
Discovery of thymosin β4 as a human exerkine and growth factor.
Gonzalez-Franquesa A, Stocks B, Borg ML, Kuefner M, Dalbram E, Nielsen TS, Agrawal A, Pankratova S, Chibalin AV, Karlsson HKR, Gheibi S, Björnholm M, Jørgensen NR, Clemmensen C, Hostrup M, Treebak JT, Krook A, Zierath JR, Deshmukh AS. Gonzalez-Franquesa A, et al. Among authors: nielsen ts. Am J Physiol Cell Physiol. 2021 Nov 1;321(5):C770-C778. doi: 10.1152/ajpcell.00263.2021. Epub 2021 Sep 8. Am J Physiol Cell Physiol. 2021. PMID: 34495765 Free article.
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