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Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness.
Obermeyer F, Jankowiak M, Barkas N, Schaffner SF, Pyle JD, Yurkovetskiy L, Bosso M, Park DJ, Babadi M, MacInnis BL, Luban J, Sabeti PC, Lemieux JE. Obermeyer F, et al. Among authors: luban j. medRxiv [Preprint]. 2022 Feb 16:2021.09.07.21263228. doi: 10.1101/2021.09.07.21263228. medRxiv. 2022. Update in: Science. 2022 Jun 17;376(6599):1327-1332. doi: 10.1126/science.abm1208. PMID: 35194619 Free PMC article. Updated. Preprint.
Vaccine Breakthrough Infection with the SARS-CoV-2 Delta or Omicron (BA.1) Variant Leads to Distinct Profiles of Neutralizing Antibody Responses.
Seaman MS, Siedner MJ, Boucau J, Lavine CL, Ghantous F, Liew MY, Mathews J, Singh A, Marino C, Regan J, Uddin R, Choudhary MC, Flynn JP, Chen G, Stuckwisch AM, Lipiner T, Kittilson A, Melberg M, Gilbert RF, Reynolds Z, Iyer SL, Chamberlin GC, Vyas TD, Vyas JM, Goldberg MB, Luban J, Li JZ, Barczak AK, Lemieux JE. Seaman MS, et al. Among authors: luban j. medRxiv [Preprint]. 2022 Mar 3:2022.03.02.22271731. doi: 10.1101/2022.03.02.22271731. medRxiv. 2022. Update in: JCI Insight. 2022 Oct 10;7(19):e159944. doi: 10.1172/jci.insight.159944. PMID: 35262094 Free PMC article. Updated. Preprint.
The 2022 RSV surge was driven by multiple viral lineages.
Adams G, Moreno GK, Petros BA, Uddin R, Levine Z, Kotzen B, Messer K, Dobbins ST, DeRuff KC, Loreth C, Brock-Fisher T, Schaffner SF, Chaluvadi S, Kanjilal S, Luban J, Ozonoff A, Park D, Turbett S, Siddle KJ, MacInnis BL, Sabeti P, Lemieux J. Adams G, et al. Among authors: luban j. medRxiv [Preprint]. 2023 Jan 5:2023.01.04.23284195. doi: 10.1101/2023.01.04.23284195. medRxiv. 2023. Update in: N Engl J Med. 2023 Apr 6;388(14):1335-1337. doi: 10.1056/NEJMc2216153. PMID: 36656774 Free PMC article. Updated. Preprint.
Natural history of Ebola virus disease in rhesus monkeys shows viral variant emergence dynamics and tissue-specific host responses.
Normandin E, Triana S, Raju SS, Lan TCT, Lagerborg K, Rudy M, Adams GC, DeRuff KC, Logue J, Liu D, Strebinger D, Rao A, Messer KS, Sacks M, Adams RD, Janosko K, Kotliar D, Shah R, Crozier I, Rinn JL, Melé M, Honko AN, Zhang F, Babadi M, Luban J, Bennett RS, Shalek AK, Barkas N, Lin AE, Hensley LE, Sabeti PC, Siddle KJ. Normandin E, et al. Among authors: luban j. Cell Genom. 2023 Nov 21;3(12):100440. doi: 10.1016/j.xgen.2023.100440. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38169842 Free PMC article.
Cyclophilin A facilitates HIV-1 integration.
Padron A, Dwivedi R, Chakraborty R, Prakash P, Kim K, Shi J, Ahn J, Pandhare J, Luban J, Aiken C, Balasubramaniam M, Dash C. Padron A, et al. Among authors: luban j. J Virol. 2024 Oct 31:e0094724. doi: 10.1128/jvi.00947-24. Online ahead of print. J Virol. 2024. PMID: 39480090
Increasing intracellular dNTP levels improves prime editing efficiency.
Liu P, Ponnienselvan K, Nyalile T, Oikemus S, Joynt AT, Iyer S, Kelly K, Guo D, Kyawe PP, Vanderleeden E, Redick SD, Huang L, Chen Z, Lee JM, Schiffer CA, Harlan DM, Wang JP, Emerson CP Jr, Lawson ND, Watts JK, Sontheimer EJ, Luban J, Wolfe SA. Liu P, et al. Among authors: luban j. Nat Biotechnol. 2024 Sep 25. doi: 10.1038/s41587-024-02405-x. Online ahead of print. Nat Biotechnol. 2024. PMID: 39322763
182 results