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Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates.
Wang L, Asare E, Shetty AC, Sanchez-Tumbaco F, Edwards MR, Saranathan R, Weinrick B, Xu J, Chen B, Bénard A, Dougan G, Leung DW, Amarasinghe GK, Chan J, Basler CF, Jacobs WR Jr, Tufariello JM. Wang L, et al. Among authors: sanchez tumbaco f. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2112608119. doi: 10.1073/pnas.2112608119. Proc Natl Acad Sci U S A. 2022. PMID: 35193958 Free PMC article.