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Page 1
The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration.
Senage T, Paul A, Le Tourneau T, Fellah-Hebia I, Vadori M, Bashir S, Galiñanes M, Bottio T, Gerosa G, Evangelista A, Badano LP, Nassi A, Costa C, Cesare G, Manji RA, Cueff de Monchy C, Piriou N, Capoulade R, Serfaty JM, Guimbretière G, Dantan E, Ruiz-Majoral A, Coste du Fou G, Leviatan Ben-Arye S, Govani L, Yehuda S, Bachar Abramovitch S, Amon R, Reuven EM, Atiya-Nasagi Y, Yu H, Iop L, Casós K, Kuguel SG, Blasco-Lucas A, Permanyer E, Sbraga F, Llatjós R, Moreno-Gonzalez G, Sánchez-Martínez M, Breimer ME, Holgersson J, Teneberg S, Pascual-Gilabert M, Nonell-Canals A, Takeuchi Y, Chen X, Mañez R, Roussel JC, Soulillou JP, Cozzi E, Padler-Karavani V. Senage T, et al. Among authors: nonell canals a. Nat Med. 2022 Feb;28(2):283-294. doi: 10.1038/s41591-022-01682-w. Epub 2022 Feb 17. Nat Med. 2022. PMID: 35177855 Free PMC article.
Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation.
Cuyàs E, Verdura S, Llorach-Parés L, Fernández-Arroyo S, Joven J, Martin-Castillo B, Bosch-Barrera J, Brunet J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA. Cuyàs E, et al. Among authors: nonell canals a. Front Endocrinol (Lausanne). 2018 Nov 6;9:657. doi: 10.3389/fendo.2018.00657. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30459716 Free PMC article.
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.
Cuyàs E, Verdura S, Llorach-Pares L, Fernández-Arroyo S, Luciano-Mateo F, Cabré N, Stursa J, Werner L, Martin-Castillo B, Viollet B, Neuzil J, Joven J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA. Cuyàs E, et al. Aging Cell. 2018 Aug;17(4):e12772. doi: 10.1111/acel.12772. Epub 2018 May 8. Aging Cell. 2018. PMID: 29740925 Free PMC article.
Silibinin is a direct inhibitor of STAT3.
Verdura S, Cuyàs E, Llorach-Parés L, Pérez-Sánchez A, Micol V, Nonell-Canals A, Joven J, Valiente M, Sánchez-Martínez M, Bosch-Barrera J, Menendez JA. Verdura S, et al. Food Chem Toxicol. 2018 Jun;116(Pt B):161-172. doi: 10.1016/j.fct.2018.04.028. Epub 2018 Apr 14. Food Chem Toxicol. 2018. PMID: 29660364
The extra virgin olive oil phenolic oleacein is a dual substrate-inhibitor of catechol-O-methyltransferase.
Cuyàs E, Verdura S, Lozano-Sánchez J, Viciano I, Llorach-Parés L, Nonell-Canals A, Bosch-Barrera J, Brunet J, Segura-Carretero A, Sanchez-Martinez M, Encinar JA, Menendez JA. Cuyàs E, et al. Among authors: nonell canals a. Food Chem Toxicol. 2019 Jun;128:35-45. doi: 10.1016/j.fct.2019.03.049. Epub 2019 Mar 29. Food Chem Toxicol. 2019. PMID: 30935952
Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets.
Cuyàs E, Castillo D, Llorach-Parés L, Lozano-Sánchez J, Verdura S, Nonell-Canals A, Brunet J, Bosch-Barrera J, Joven J, Valdés R, Sanchez-Martinez M, Segura-Carretero A, Menendez JA. Cuyàs E, et al. Among authors: nonell canals a. Food Chem Toxicol. 2019 Sep;131:110529. doi: 10.1016/j.fct.2019.05.037. Epub 2019 May 29. Food Chem Toxicol. 2019. PMID: 31150784
19 results