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SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice.
Bresque M, Cal K, Pérez-Torrado V, Colman L, Rodríguez-Duarte J, Vilaseca C, Santos L, Garat MP, Ruiz S, Evans F, Dapueto R, Contreras P, Calliari A, Escande C. Bresque M, et al. Among authors: contreras p. J Biol Chem. 2022 Mar;298(3):101711. doi: 10.1016/j.jbc.2022.101711. Epub 2022 Feb 9. J Biol Chem. 2022. PMID: 35150745 Free PMC article.
A novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo.
Santos L, Colman L, Contreras P, Chini CC, Carlomagno A, Leyva A, Bresque M, Marmisolle I, Quijano C, Durán R, Irigoín F, Prieto-Echagüe V, Vendelbo MH, Sotelo-Silveira JR, Chini EN, Badano JL, Calliari AJ, Escande C. Santos L, et al. Among authors: contreras p. Sci Rep. 2019 Oct 7;9(1):14381. doi: 10.1038/s41598-019-50789-7. Sci Rep. 2019. PMID: 31591441 Free PMC article.
Benefits in cardiac function by CD38 suppression: Improvement in NAD+ levels, exercise capacity, heart rate variability and protection against catecholamine-induced ventricular arrhythmias.
Agorrody G, Peclat TR, Peluso G, Gonano LA, Santos L, van Schooten W, Chini CCS, Escande C, Chini EN, Contreras P. Agorrody G, et al. Among authors: contreras p. J Mol Cell Cardiol. 2022 May;166:11-22. doi: 10.1016/j.yjmcc.2022.01.008. Epub 2022 Feb 1. J Mol Cell Cardiol. 2022. PMID: 35114253 Free PMC article.
Right atrium cholinergic deficit in septic rats.
Contreras P, Migliaro ER, Suhr B. Contreras P, et al. Auton Neurosci. 2014 Feb;180:17-23. doi: 10.1016/j.autneu.2013.10.002. Epub 2013 Oct 11. Auton Neurosci. 2014. PMID: 24269487
Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
Mazzocchi G, Sommese L, Palomeque J, Felice JI, Di Carlo MN, Fainstein D, Gonzalez P, Contreras P, Skapura D, McCauley MD, Lascano EC, Negroni JA, Kranias EG, Wehrens XH, Valverde CA, Mattiazzi A. Mazzocchi G, et al. Among authors: contreras p. J Physiol. 2016 Jun 1;594(11):3005-30. doi: 10.1113/JP271622. Epub 2016 Feb 2. J Physiol. 2016. PMID: 26695843 Free PMC article.
237 results