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Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription.
Minisini M, Di Giorgio E, Kerschbamer E, Dalla E, Faggiani M, Franforte E, Meyer-Almes FJ, Ragno R, Antonini L, Mai A, Fiorentino F, Rotili D, Chinellato M, Perin S, Cendron L, Weichenberger CX, Angelini A, Brancolini C. Minisini M, et al. Among authors: fiorentino f. Nucleic Acids Res. 2022 Mar 21;50(5):2566-2586. doi: 10.1093/nar/gkac081. Nucleic Acids Res. 2022. PMID: 35150567 Free PMC article.
Lysine Acetyltransferase Inhibitors From Natural Sources.
Fiorentino F, Mai A, Rotili D. Fiorentino F, et al. Front Pharmacol. 2020 Aug 12;11:1243. doi: 10.3389/fphar.2020.01243. eCollection 2020. Front Pharmacol. 2020. PMID: 32903408 Free PMC article. Review.
The Two-Faced Role of SIRT6 in Cancer.
Fiorentino F, Carafa V, Favale G, Altucci L, Mai A, Rotili D. Fiorentino F, et al. Cancers (Basel). 2021 Mar 8;13(5):1156. doi: 10.3390/cancers13051156. Cancers (Basel). 2021. PMID: 33800266 Free PMC article. Review.
Emerging Therapeutic Potential of SIRT6 Modulators.
Fiorentino F, Mai A, Rotili D. Fiorentino F, et al. J Med Chem. 2021 Jul 22;64(14):9732-9758. doi: 10.1021/acs.jmedchem.1c00601. Epub 2021 Jul 2. J Med Chem. 2021. PMID: 34213345 Free PMC article. Review.
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.
Menna M, Fiorentino F, Marrocco B, Lucidi A, Tomassi S, Cilli D, Romanenghi M, Cassandri M, Pomella S, Pezzella M, Del Bufalo D, Zeya Ansari MS, Tomašević N, Mladenović M, Viviano M, Sbardella G, Rota R, Trisciuoglio D, Minucci S, Mattevi A, Rotili D, Mai A. Menna M, et al. Among authors: fiorentino f. Eur J Med Chem. 2022 Jul 5;237:114410. doi: 10.1016/j.ejmech.2022.114410. Epub 2022 Apr 27. Eur J Med Chem. 2022. PMID: 35525212
Sirtuin modulators: past, present, and future perspectives.
Fiorentino F, Mautone N, Menna M, D'Acunzo F, Mai A, Rotili D. Fiorentino F, et al. Future Med Chem. 2022 Jun;14(12):915-939. doi: 10.4155/fmc-2022-0031. Epub 2022 May 18. Future Med Chem. 2022. PMID: 35583203 Free PMC article. Review.
346 results