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Colorectal cancer development is affected by the ECM molecule EMILIN-2 hinging on macrophage polarization via the TLR-4/MyD88 pathway.
Andreuzzi E, Fejza A, Polano M, Poletto E, Camicia L, Carobolante G, Tarticchio G, Todaro F, Di Carlo E, Scarpa M, Scarpa M, Paulitti A, Capuano A, Canzonieri V, Maiero S, Fornasarig M, Cannizzaro R, Doliana R, Colombatti A, Spessotto P, Mongiat M. Andreuzzi E, et al. Among authors: capuano a. J Exp Clin Cancer Res. 2022 Feb 11;41(1):60. doi: 10.1186/s13046-022-02271-y. J Exp Clin Cancer Res. 2022. PMID: 35148799 Free PMC article.
The solution structure of EMILIN1 globular C1q domain reveals a disordered insertion necessary for interaction with the alpha4beta1 integrin.
Verdone G, Doliana R, Corazza A, Colebrooke SA, Spessotto P, Bot S, Bucciotti F, Capuano A, Silvestri A, Viglino P, Campbell ID, Colombatti A, Esposito G. Verdone G, et al. Among authors: capuano a. J Biol Chem. 2008 Jul 4;283(27):18947-56. doi: 10.1074/jbc.M801085200. Epub 2008 May 7. J Biol Chem. 2008. PMID: 18463100 Free article.
607 results