Vikram A - Search Results

1

γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet.

Gaddam RR, Dhuri K, Kim YR, Jacobs JS, Kumar V, Li Q, Irani K, Bahal R, Vikram A. Gaddam RR, et al. Among authors: vikram a. J Med Chem. 2022 Feb 24;65(4):3332-3342. doi: 10.1021/acs.jmedchem.1c01831. Epub 2022 Feb 8. J Med Chem. 2022. PMID: 35133835 Free PMC article.

2

Urethral steinstrasse causing acute urinary retention.

Vaddi SP, Devraj R, Reddy V, Vikram A, Dayapule S, Munisami R. Vaddi SP, et al. Among authors: vikram a. Urology. 2011 Mar;77(3):594-5. doi: 10.1016/j.urology.2010.04.003. Epub 2010 Dec 24. Urology. 2011. PMID: 21186051

3

Histone and DNA methylation-mediated epigenetic downregulation of endothelial Kruppel-like factor 2 by low-density lipoprotein cholesterol.

Kumar A, Kumar S, Vikram A, Hoffman TA, Naqvi A, Lewarchik CM, Kim YR, Irani K. Kumar A, et al. Among authors: vikram a. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1936-42. doi: 10.1161/ATVBAHA.113.301765. Epub 2013 May 30. Arterioscler Thromb Vasc Biol. 2013. PMID: 23723375

4

P66Shc mediates increased platelet activation and aggregation in hypercholesterolemia.

Kumar S, Vikram A, Kim YR, S Jacobs J, Irani K. Kumar S, et al. Among authors: vikram a. Biochem Biophys Res Commun. 2014 Jul 11;449(4):496-501. doi: 10.1016/j.bbrc.2014.05.029. Epub 2014 May 15. Biochem Biophys Res Commun. 2014. PMID: 24845561

5

Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.

Vikram A, Kim YR, Kumar S, Naqvi A, Hoffman TA, Kumar A, Miller FJ Jr, Kim CS, Irani K. Vikram A, et al. Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2301-9. doi: 10.1161/ATVBAHA.114.304338. Epub 2014 Aug 21. Arterioscler Thromb Vasc Biol. 2014. PMID: 25147340 Free PMC article.

6

Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1.

Vikram A, Kim YR, Kumar S, Li Q, Kassan M, Jacobs JS, Irani K. Vikram A, et al. Nat Commun. 2016 Sep 2;7:12565. doi: 10.1038/ncomms12565. Nat Commun. 2016. PMID: 27586459 Free PMC article.

7

P66Shc-Induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1.

Li Q, Kim YR, Vikram A, Kumar S, Kassan M, Gabani M, Lee SK, Jacobs JS, Irani K. Li Q, et al. Among authors: vikram a. Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2394-2403. doi: 10.1161/ATVBAHA.116.308321. Epub 2016 Oct 27. Arterioscler Thromb Vasc Biol. 2016. PMID: 27789474 Free PMC article.

8

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction.

Kumar S, Kim YR, Vikram A, Naqvi A, Li Q, Kassan M, Kumar V, Bachschmid MM, Jacobs JS, Kumar A, Irani K. Kumar S, et al. Among authors: vikram a. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1714-1719. doi: 10.1073/pnas.1614112114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137876 Free PMC article.

9

Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress.

Kassan M, Vikram A, Kim YR, Li Q, Kassan A, Patel HH, Kumar S, Gabani M, Liu J, Jacobs JS, Irani K. Kassan M, et al. Among authors: vikram a. Sci Rep. 2017 Feb 9;7:42265. doi: 10.1038/srep42265. Sci Rep. 2017. PMID: 28181559 Free PMC article.

10

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.

Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K. Vikram A, et al. Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191886 Free PMC article.

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