Serganov A - Search Results

1

A distinct RNA recognition mechanism governs Np₄ decapping by RppH.

Levenson-Palmer R, Luciano DJ, Vasilyev N, Nuthanakanti A, Serganov A, Belasco JG. Levenson-Palmer R, et al. Among authors: serganov a. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2117318119. doi: 10.1073/pnas.2117318119. Proc Natl Acad Sci U S A. 2022. PMID: 35131855 Free PMC article.

2

Structures of RNA complexes with the Escherichia coli RNA pyrophosphohydrolase RppH unveil the basis for specific 5'-end-dependent mRNA decay.

Vasilyev N, Serganov A. Vasilyev N, et al. Among authors: serganov a. J Biol Chem. 2015 Apr 10;290(15):9487-99. doi: 10.1074/jbc.M114.634824. Epub 2015 Feb 5. J Biol Chem. 2015. PMID: 25657011 Free PMC article.

3

Preparation of Short 5'-Triphosphorylated Oligoribonucleotides for Crystallographic and Biochemical Studies.

Vasilyev N, Serganov A. Vasilyev N, et al. Among authors: serganov a. Methods Mol Biol. 2016;1320:11-20. doi: 10.1007/978-1-4939-2763-0_2. Methods Mol Biol. 2016. PMID: 26227034

4

Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.

Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A. Vasilyev N, et al. Among authors: serganov a. Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5391-400. doi: 10.1073/pnas.1515737112. Epub 2015 Sep 15. Proc Natl Acad Sci U S A. 2015. PMID: 26374839 Free PMC article.

5

A Novel RNA Phosphorylation State Enables 5' End-Dependent Degradation in Escherichia coli.

Luciano DJ, Vasilyev N, Richards J, Serganov A, Belasco JG. Luciano DJ, et al. Among authors: serganov a. Mol Cell. 2017 Jul 6;67(1):44-54.e6. doi: 10.1016/j.molcel.2017.05.035. Epub 2017 Jun 29. Mol Cell. 2017. PMID: 28673541 Free PMC article.

6

Importance of a diphosphorylated intermediate for RppH-dependent RNA degradation.

Luciano DJ, Vasilyev N, Richards J, Serganov A, Belasco JG. Luciano DJ, et al. Among authors: serganov a. RNA Biol. 2018;15(6):703-706. doi: 10.1080/15476286.2018.1460995. Epub 2018 May 29. RNA Biol. 2018. PMID: 29619898 Free PMC article.

7

Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF.

Gao A, Vasilyev N, Luciano DJ, Levenson-Palmer R, Richards J, Marsiglia WM, Traaseth NJ, Belasco JG, Serganov A. Gao A, et al. Among authors: serganov a. Nucleic Acids Res. 2018 Jul 27;46(13):6841-6856. doi: 10.1093/nar/gky327. Nucleic Acids Res. 2018. PMID: 29733359 Free PMC article.

8

Noncanonical features and modifications on the 5'-end of bacterial sRNAs and mRNAs.

Vasilyev N, Gao A, Serganov A. Vasilyev N, et al. Among authors: serganov a. Wiley Interdiscip Rev RNA. 2019 Mar;10(2):e1509. doi: 10.1002/wrna.1509. Epub 2018 Oct 1. Wiley Interdiscip Rev RNA. 2019. PMID: 30276982 Free PMC article. Review.

9

Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH.

Gao A, Vasilyev N, Kaushik A, Duan W, Serganov A. Gao A, et al. Among authors: serganov a. Nucleic Acids Res. 2020 Apr 17;48(7):3776-3788. doi: 10.1093/nar/gkaa024. Nucleic Acids Res. 2020. PMID: 31960065 Free PMC article.

10

Inhibitors of bacterial H₂S biogenesis targeting antibiotic resistance and tolerance.

Shatalin K, Nuthanakanti A, Kaushik A, Shishov D, Peselis A, Shamovsky I, Pani B, Lechpammer M, Vasilyev N, Shatalina E, Rebatchouk D, Mironov A, Fedichev P, Serganov A, Nudler E. Shatalin K, et al. Among authors: serganov a. Science. 2021 Jun 11;372(6547):1169-1175. doi: 10.1126/science.abd8377. Science. 2021. PMID: 34112687 Free PMC article.

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