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Page 1
Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2.
Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Ardanuy J, Taylor L, Lee JS, Li M, Lee E, Shoffler C, Petucci C, Constant S, Ferrer M, Thaiss CA, Frieman MB, Cherry S. Schultz DC, et al. Among authors: kamalia b. Nature. 2022 Apr;604(7904):134-140. doi: 10.1038/s41586-022-04482-x. Epub 2022 Feb 7. Nature. 2022. PMID: 35130559 Free PMC article.
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2.
Dittmar M, Lee JS, Whig K, Segrist E, Li M, Kamalia B, Castellana L, Ayyanathan K, Cardenas-Diaz FL, Morrisey EE, Truitt R, Yang W, Jurado K, Samby K, Ramage H, Schultz DC, Cherry S. Dittmar M, et al. Among authors: kamalia b. Cell Rep. 2021 Apr 6;35(1):108959. doi: 10.1016/j.celrep.2021.108959. Epub 2021 Mar 23. Cell Rep. 2021. PMID: 33811811 Free PMC article.
Pharmacological activation of STING blocks SARS-CoV-2 infection.
Li M, Ferretti M, Ying B, Descamps H, Lee E, Dittmar M, Lee JS, Whig K, Kamalia B, Dohnalová L, Uhr G, Zarkoob H, Chen YC, Ramage H, Ferrer M, Lynch K, Schultz DC, Thaiss CA, Diamond MS, Cherry S. Li M, et al. Among authors: kamalia b. Sci Immunol. 2021 May 18;6(59):eabi9007. doi: 10.1126/sciimmunol.abi9007. Sci Immunol. 2021. PMID: 34010142 Free PMC article.
Nucleoside analogs NM107 and AT-527 are antiviral against rubella virus.
Dittmar M, Whig K, Miller J, Kamalia B, Suppiah S, Perelygina L, Sullivan KE, Schultz DC, Cherry S. Dittmar M, et al. Among authors: kamalia b. PNAS Nexus. 2023 Aug 3;2(9):pgad256. doi: 10.1093/pnasnexus/pgad256. eCollection 2023 Sep. PNAS Nexus. 2023. PMID: 37674858 Free PMC article.
Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection.
Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Castellana L, Lee JS, Li M, Lee E, Constant S, Ferrer M, Thaiss CA, Frieman MB, Cherry S. Schultz DC, et al. Among authors: kamalia b. bioRxiv [Preprint]. 2021 Jun 24:2021.06.24.449811. doi: 10.1101/2021.06.24.449811. bioRxiv. 2021. Update in: Nature. 2022 Apr;604(7904):134-140. doi: 10.1038/s41586-022-04482-x. PMID: 34189531 Free PMC article. Updated. Preprint.