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Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.
Campbell MR, Ruiz-Saenz A, Peterson E, Agnew C, Ayaz P, Garfinkle S, Littlefield P, Steri V, Oeffinger J, Sampang M, Shan Y, Shaw DE, Jura N, Moasser MM. Campbell MR, et al. Among authors: shan y. Cell Rep. 2022 Feb 1;38(5):110291. doi: 10.1016/j.celrep.2021.110291. Cell Rep. 2022. PMID: 35108525 Free PMC article.
Mechanism of Na+/H+ antiporting.
Arkin IT, Xu H, Jensen MØ, Arbely E, Bennett ER, Bowers KJ, Chow E, Dror RO, Eastwood MP, Flitman-Tene R, Gregersen BA, Klepeis JL, Kolossváry I, Shan Y, Shaw DE. Arkin IT, et al. Among authors: shan y. Science. 2007 Aug 10;317(5839):799-803. doi: 10.1126/science.1142824. Science. 2007. PMID: 17690293
Atomic-level characterization of the structural dynamics of proteins.
Shaw DE, Maragakis P, Lindorff-Larsen K, Piana S, Dror RO, Eastwood MP, Bank JA, Jumper JM, Salmon JK, Shan Y, Wriggers W. Shaw DE, et al. Among authors: shan y. Science. 2010 Oct 15;330(6002):341-6. doi: 10.1126/science.1187409. Science. 2010. PMID: 20947758
How does a drug molecule find its target binding site?
Shan Y, Kim ET, Eastwood MP, Dror RO, Seeliger MA, Shaw DE. Shan Y, et al. J Am Chem Soc. 2011 Jun 22;133(24):9181-3. doi: 10.1021/ja202726y. Epub 2011 May 13. J Am Chem Soc. 2011. PMID: 21545110 Free PMC article.
Pathway and mechanism of drug binding to G-protein-coupled receptors.
Dror RO, Pan AC, Arlow DH, Borhani DW, Maragakis P, Shan Y, Xu H, Shaw DE. Dror RO, et al. Among authors: shan y. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13118-23. doi: 10.1073/pnas.1104614108. Epub 2011 Jul 21. Proc Natl Acad Sci U S A. 2011. PMID: 21778406 Free PMC article.
3,598 results