Agnew C - Search Results

1

Targetable HER3 functions driving tumorigenic signaling in HER2-amplified cancers.

Campbell MR, Ruiz-Saenz A, Peterson E, Agnew C, Ayaz P, Garfinkle S, Littlefield P, Steri V, Oeffinger J, Sampang M, Shan Y, Shaw DE, Jura N, Moasser MM. Campbell MR, et al. Among authors: agnew c. Cell Rep. 2022 Feb 1;38(5):110291. doi: 10.1016/j.celrep.2021.110291. Cell Rep. 2022. PMID: 35108525 Free PMC article.

2

EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms.

van Lengerich B, Agnew C, Puchner EM, Huang B, Jura N. van Lengerich B, et al. Among authors: agnew c. Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2836-E2845. doi: 10.1073/pnas.1617994114. Epub 2017 Mar 20. Proc Natl Acad Sci U S A. 2017. PMID: 28320942 Free PMC article.

3

Structural basis for ALK2/BMPR2 receptor complex signaling through kinase domain oligomerization.

Agnew C, Ayaz P, Kashima R, Loving HS, Ghatpande P, Kung JE, Underbakke ES, Shan Y, Shaw DE, Hata A, Jura N. Agnew C, et al. Nat Commun. 2021 Aug 16;12(1):4950. doi: 10.1038/s41467-021-25248-5. Nat Commun. 2021. PMID: 34400635 Free PMC article.

4

Switching on BTK-One Domain at a Time.

Agnew C, Jura N. Agnew C, et al. Structure. 2017 Oct 3;25(10):1469-1470. doi: 10.1016/j.str.2017.09.012. Epub 2017 Oct 3. Structure. 2017. PMID: 28978404 Free article.

5

The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region.

Agnew C, Liu L, Liu S, Xu W, You L, Yeung W, Kannan N, Jablons D, Jura N. Agnew C, et al. J Biol Chem. 2019 Sep 13;294(37):13545-13559. doi: 10.1074/jbc.RA119.009725. Epub 2019 Jul 24. J Biol Chem. 2019. PMID: 31341017 Free PMC article.

6

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids.

Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. Lo M, et al. Among authors: agnew c. Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. Nat Commun. 2022. PMID: 35504891 Free PMC article.

7

Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.

Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N. Ruiz K, et al. Among authors: agnew c. Nat Commun. 2019 Jan 31;10(1):531. doi: 10.1038/s41467-019-08393-w. Nat Commun. 2019. PMID: 30705304 Free PMC article.

8

Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation.

Seidler DG, Goldoni S, Agnew C, Cardi C, Thakur ML, Owens RT, McQuillan DJ, Iozzo RV. Seidler DG, et al. Among authors: agnew c. J Biol Chem. 2006 Sep 8;281(36):26408-18. doi: 10.1074/jbc.M602853200. Epub 2006 Jul 11. J Biol Chem. 2006. PMID: 16835231 Free article.

9

Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.

Agnew C, Borodina E, Zaccai NR, Conners R, Burton NM, Vicary JA, Cole DK, Antognozzi M, Virji M, Brady RL. Agnew C, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15174-8. doi: 10.1073/pnas.1106341108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876142 Free PMC article.

10

A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity.

Goldoni S, Iozzo RA, Kay P, Campbell S, McQuillan A, Agnew C, Zhu JX, Keene DR, Reed CC, Iozzo RV. Goldoni S, et al. Among authors: agnew c. Oncogene. 2007 Jan 18;26(3):368-81. doi: 10.1038/sj.onc.1209803. Epub 2006 Jul 17. Oncogene. 2007. PMID: 16847455

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