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Photoswitchable inhibitors of human β-glucocerebrosidase.
Org Biomol Chem. 2022 Feb 23;20(8):1637-1641. doi: 10.1039/d1ob02159a.
Org Biomol Chem. 2022.
PMID: 35107482
Synthesis of "All-Cis" Trihydroxypiperidines from a Carbohydrate-Derived Ketone: Hints for the Design of New β-Gal and GCase Inhibitors.
Davighi MG, Clemente F, Matassini C, Morrone A, Goti A, Martínez-Bailén M, Cardona F.
Davighi MG, et al.
Molecules. 2020 Oct 2;25(19):4526. doi: 10.3390/molecules25194526.
Molecules. 2020.
PMID: 33023214
Free PMC article.
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Light-Triggered Control of Glucocerebrosidase Inhibitors: Towards Photoswitchable Pharmacological Chaperones.
Clemente F, Davighi MG, Matassini C, Cardona F, Goti A, Morrone A, Paoli P, Tejero T, Merino P, Cacciarini M.
Clemente F, et al. Among authors: davighi mg.
Chemistry. 2023 Apr 3;29(19):e202203841. doi: 10.1002/chem.202203841. Epub 2023 Mar 1.
Chemistry. 2023.
PMID: 36598148
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Mono- and three-tailed sugar and iminosugar decorated benzenesulfonamide carbonic anhydrase inhibitors.
Davighi MG, Matassini C, Goti A, Ferraroni M, Angeli A, Supuran CT, Cardona F.
Davighi MG, et al.
Org Biomol Chem. 2023 May 31;21(21):4491-4503. doi: 10.1039/d3ob00529a.
Org Biomol Chem. 2023.
PMID: 37198937
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pH-Responsive Trihydroxylated Piperidines Rescue The Glucocerebrosidase Activity in Human Fibroblasts Bearing The Neuronopathic Gaucher-Related L444P/L444P Mutations in GBA1 Gene.
Davighi MG, Matassini C, Clemente F, Paoli P, Morrone A, Cacciarini M, Goti A, Cardona F.
Davighi MG, et al.
Chembiochem. 2024 Jan 2;25(1):e202300730. doi: 10.1002/cbic.202300730. Epub 2023 Nov 13.
Chembiochem. 2024.
PMID: 37877519
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Iminosugar-Dihydroazulenes as Mutant L444P Glucocerebrosidase Enhancers.
Davighi MG, Clemente F, Andreasen ES, Nielsen MB, Matassini C, Goti A, Morrone A, Paoli P, Cardona F, Cacciarini M.
Davighi MG, et al.
Chem Biodivers. 2024 Aug;21(8):e202401104. doi: 10.1002/cbdv.202401104. Epub 2024 Jul 23.
Chem Biodivers. 2024.
PMID: 38847390
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