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161 results

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Page 1
TGF-β-activated kinase-1 inhibitor LL-Z1640-2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF-α and RANKL expression.
Tenshin H, Teramachi J, Ashtar M, Hiasa M, Inoue Y, Oda A, Tanimoto K, Shimizu S, Higa Y, Harada T, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Sebe M, Tsutsumi R, Sakaue H, Endo I, Matsumoto T, Tanaka E, Abe M. Tenshin H, et al. Among authors: higa y. Clin Transl Immunology. 2022 Jan 19;11(1):e1371. doi: 10.1002/cti2.1371. eCollection 2022. Clin Transl Immunology. 2022. PMID: 35079379 Free PMC article.
The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat.
Ashtar M, Tenshin H, Teramachi J, Bat-Erdene A, Hiasa M, Oda A, Tanimoto K, Shimizu S, Higa Y, Harada T, Oura M, Sogabe K, Nakamura S, Fujii S, Sumitani R, Miki H, Udaka K, Takahashi M, Kagawa K, Endo I, Tanaka E, Matsumoto T, Abe M. Ashtar M, et al. Among authors: higa y. Cancers (Basel). 2020 Apr 9;12(4):929. doi: 10.3390/cancers12040929. Cancers (Basel). 2020. PMID: 32283857 Free PMC article.
Mechanical unloading aggravates bone destruction and tumor expansion in myeloma.
Tanimoto K, Hiasa M, Tenshin H, Teramachi J, Oda A, Harada T, Higa Y, Sogabe K, Oura M, Sumitani R, Hara T, Endo I, Matsumoto T, Tanaka E, Abe M. Tanimoto K, et al. Among authors: higa y. Haematologica. 2022 Mar 1;107(3):744-749. doi: 10.3324/haematol.2021.278295. Haematologica. 2022. PMID: 34788982 Free PMC article. No abstract available.
Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis.
Dong B, Hiasa M, Higa Y, Ohnishi Y, Endo I, Kondo T, Takashi Y, Tsoumpra M, Kainuma R, Sawatsubashi S, Kiyonari H, Shioi G, Sakaue H, Nakashima T, Kato S, Abe M, Fukumoto S, Matsumoto T. Dong B, et al. Among authors: higa y. Nat Commun. 2022 Nov 23;13(1):7194. doi: 10.1038/s41467-022-34869-3. Nat Commun. 2022. PMID: 36424386 Free PMC article.
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2.
Higa Y, Hiasa M, Tenshin H, Nakaue E, Tanaka M, Kim S, Nakagawa M, Shimizu S, Tanimoto K, Teramachi J, Harada T, Oda A, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Matsumoto T, Tanaka E, Abe M. Higa Y, et al. Antioxidants (Basel). 2023 Jan 5;12(1):133. doi: 10.3390/antiox12010133. Antioxidants (Basel). 2023. PMID: 36670994 Free PMC article.
Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors.
Nakaue E, Teramachi J, Tenshin H, Hiasa M, Harada T, Oda A, Inoue Y, Shimizu S, Higa Y, Sogabe K, Oura M, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Tanaka E, Abe M. Nakaue E, et al. Among authors: higa y. Int J Hematol. 2023 Jul;118(1):88-98. doi: 10.1007/s12185-023-03601-2. Epub 2023 Apr 11. Int J Hematol. 2023. PMID: 37039914 Free PMC article.
Acute accumulation of PIM2 and NRF2 and recovery of β5 subunit activity mitigate multiple myeloma cell susceptibility to proteasome inhibitors.
Sogabe K, Nakamura S, Higa Y, Miki H, Oda A, Maruhashi T, Sumitani R, Oura M, Takahashi M, Nakamura M, Maeda Y, Hara T, Yamagami H, Fujii S, Kagawa K, Ozaki S, Kurahashi K, Endo I, Aihara KI, Nakaue E, Hiasa M, Teramachi J, Harada T, Abe M. Sogabe K, et al. Among authors: higa y. Int J Hematol. 2024 Mar;119(3):303-315. doi: 10.1007/s12185-023-03705-9. Epub 2024 Jan 21. Int J Hematol. 2024. PMID: 38245883
Inflammatory Cytokine-Induced Muscle Atrophy and Weakness Can Be Ameliorated by an Inhibition of TGF-β-Activated Kinase-1.
Kanai M, Ganbaatar B, Endo I, Ohnishi Y, Teramachi J, Tenshin H, Higa Y, Hiasa M, Mitsui Y, Hara T, Masuda S, Yamagami H, Yamaguchi Y, Aihara KI, Sebe M, Tsutsumi R, Sakaue H, Matsumoto T, Abe M. Kanai M, et al. Among authors: higa y. Int J Mol Sci. 2024 May 24;25(11):5715. doi: 10.3390/ijms25115715. Int J Mol Sci. 2024. PMID: 38891908 Free PMC article.
Genetic, phylogenetic, and serological analysis of a Getah virus strain isolated from Culex tritaeniorhynchus mosquitoes in Nagasaki, Japan in 2022.
Matsumura R, Bannai H, Nemoto M, Higa Y, Kai I, Sasaki T, Futami K, Yoshikawa A, Fujita R, Hino M, Nagata K, Kuwata R, Kaku Y, Kobayashi D, Minakawa N, Kasai S, Itoyama K, Maeda K, Isawa H. Matsumura R, et al. Among authors: higa y. Jpn J Infect Dis. 2024 Nov 29. doi: 10.7883/yoken.JJID.2024.250. Online ahead of print. Jpn J Infect Dis. 2024. PMID: 39617482
161 results