Mou H - Search Results

1

Identification of potent small molecule inhibitors of SARS-CoV-2 entry.

Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. Among authors: mou h. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.

2

Conditional Regulation of Gene Expression by Ligand-Induced Occlusion of a MicroRNA Target Sequence.

Mou H, Zhong G, Gardner MR, Wang H, Wang YW, Cheng D, Farzan M. Mou H, et al. Mol Ther. 2018 May 2;26(5):1277-1286. doi: 10.1016/j.ymthe.2018.02.021. Epub 2018 Feb 27. Mol Ther. 2018. PMID: 29567311 Free PMC article.

3

A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo.

Zhong G, Wang H, He W, Li Y, Mou H, Tickner ZJ, Tran MH, Ou T, Yin Y, Diao H, Farzan M. Zhong G, et al. Among authors: mou h. Nat Biotechnol. 2020 Feb;38(2):169-175. doi: 10.1038/s41587-019-0357-y. Epub 2019 Dec 23. Nat Biotechnol. 2020. PMID: 31873216 Free PMC article.

4

The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity.

Zhang L, Jackson CB, Mou H, Ojha A, Rangarajan ES, Izard T, Farzan M, Choe H. Zhang L, et al. Among authors: mou h. bioRxiv [Preprint]. 2020 Jun 12:2020.06.12.148726. doi: 10.1101/2020.06.12.148726. bioRxiv. 2020. Update in: Nat Commun. 2020 Nov 26;11(1):6013. doi: 10.1038/s41467-020-19808-4 PMID: 32587973 Free PMC article. Updated. Preprint.

5

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.

Zhang L, Jackson CB, Mou H, Ojha A, Peng H, Quinlan BD, Rangarajan ES, Pan A, Vanderheiden A, Suthar MS, Li W, Izard T, Rader C, Farzan M, Choe H. Zhang L, et al. Among authors: mou h. Nat Commun. 2020 Nov 26;11(1):6013. doi: 10.1038/s41467-020-19808-4. Nat Commun. 2020. PMID: 33243994 Free PMC article.

6

Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2.

Ou T, Mou H, Zhang L, Ojha A, Choe H, Farzan M. Ou T, et al. Among authors: mou h. PLoS Pathog. 2021 Jan 19;17(1):e1009212. doi: 10.1371/journal.ppat.1009212. eCollection 2021 Jan. PLoS Pathog. 2021. PMID: 33465165 Free PMC article.

7

A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020.

Tran MH, Park H, Nobles CL, Karunadharma P, Pan L, Zhong G, Wang H, He W, Ou T, Crynen G, Sheptack K, Stiskin I, Mou H, Farzan M. Tran MH, et al. Among authors: mou h. Mol Ther Nucleic Acids. 2021 Feb 18;24:40-53. doi: 10.1016/j.omtn.2021.02.012. eCollection 2021 Jun 4. Mol Ther Nucleic Acids. 2021. PMID: 33738137 Free PMC article.

8

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

Mou H, Quinlan BD, Peng H, Liu G, Guo Y, Peng S, Zhang L, Davis-Gardner ME, Gardner MR, Crynen G, DeVaux LB, Voo ZX, Bailey CC, Alpert MD, Rader C, Gack MU, Choe H, Farzan M. Mou H, et al. PLoS Pathog. 2021 Apr 9;17(4):e1009501. doi: 10.1371/journal.ppat.1009501. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33836016 Free PMC article.

9

An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccines.

Guo Y, He W, Mou H, Zhang L, Chang J, Peng S, Ojha A, Tavora R, Parcells MS, Luo G, Li W, Zhong G, Choe H, Farzan M, Quinlan BD. Guo Y, et al. Among authors: mou h. mBio. 2021 May 11;12(3):e00930-21. doi: 10.1128/mBio.00930-21. mBio. 2021. PMID: 33975938 Free PMC article.

10

Rapid, simplified whole blood-based multiparameter assay to quantify and phenotype SARS-CoV-2-specific T-cells.

Riou C, Schäfer G, du Bruyn E, Goliath RT, Stek C, Mou H, Hung D, Wilkinson KA, Wilkinson RJ. Riou C, et al. Among authors: mou h. Eur Respir J. 2022 Jan 13;59(1):2100285. doi: 10.1183/13993003.00285-2021. Print 2022 Jan. Eur Respir J. 2022. PMID: 34140294 Free PMC article.

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