Farzan M - Search Results

1

Identification of potent small molecule inhibitors of SARS-CoV-2 entry.

Mediouni S, Mou H, Otsuka Y, Jablonski JA, Adcock RS, Batra L, Chung DH, Rood C, de Vera IMS, Rahaim R Jr, Ullah S, Yu X, Getmanenko YA, Kennedy NM, Wang C, Nguyen TT, Hull M, Chen E, Bannister TD, Baillargeon P, Scampavia L, Farzan M, Valente ST, Spicer TP. Mediouni S, et al. Among authors: farzan m. SLAS Discov. 2022 Jan;27(1):8-19. doi: 10.1016/j.slasd.2021.10.012. Epub 2021 Oct 23. SLAS Discov. 2022. PMID: 35058179 Free PMC article.

2

Identification of a new region of SARS-CoV S protein critical for viral entry.

Guo Y, Tisoncik J, McReynolds S, Farzan M, Prabhakar BS, Gallagher T, Rong L, Caffrey M. Guo Y, et al. Among authors: farzan m. J Mol Biol. 2009 Dec 11;394(4):600-5. doi: 10.1016/j.jmb.2009.10.032. Epub 2009 Oct 21. J Mol Biol. 2009. PMID: 19853613 Free PMC article.

3

Conditional Regulation of Gene Expression by Ligand-Induced Occlusion of a MicroRNA Target Sequence.

Mou H, Zhong G, Gardner MR, Wang H, Wang YW, Cheng D, Farzan M. Mou H, et al. Among authors: farzan m. Mol Ther. 2018 May 2;26(5):1277-1286. doi: 10.1016/j.ymthe.2018.02.021. Epub 2018 Feb 27. Mol Ther. 2018. PMID: 29567311 Free PMC article.

4

Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies.

Otsuka Y, Schmitt K, Quinlan BD, Gardner MR, Alfant B, Reich A, Farzan M, Choe H. Otsuka Y, et al. Among authors: farzan m. PLoS Pathog. 2018 Aug 20;14(8):e1007238. doi: 10.1371/journal.ppat.1007238. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30125330 Free PMC article.

5

A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo.

Zhong G, Wang H, He W, Li Y, Mou H, Tickner ZJ, Tran MH, Ou T, Yin Y, Diao H, Farzan M. Zhong G, et al. Among authors: farzan m. Nat Biotechnol. 2020 Feb;38(2):169-175. doi: 10.1038/s41587-019-0357-y. Epub 2019 Dec 23. Nat Biotechnol. 2020. PMID: 31873216 Free PMC article.

6

The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity.

Zhang L, Jackson CB, Mou H, Ojha A, Rangarajan ES, Izard T, Farzan M, Choe H. Zhang L, et al. Among authors: farzan m. bioRxiv [Preprint]. 2020 Jun 12:2020.06.12.148726. doi: 10.1101/2020.06.12.148726. bioRxiv. 2020. Update in: Nat Commun. 2020 Nov 26;11(1):6013. doi: 10.1038/s41467-020-19808-4 PMID: 32587973 Free PMC article. Updated. Preprint.

7

SARS-CoV-2 and Three Related Coronaviruses Utilize Multiple ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig.

Li Y, Wang H, Tang X, Fang S, Ma D, Du C, Wang Y, Pan H, Yao W, Zhang R, Zou X, Zheng J, Xu L, Farzan M, Zhong G. Li Y, et al. Among authors: farzan m. J Virol. 2020 Oct 27;94(22):e01283-20. doi: 10.1128/JVI.01283-20. Print 2020 Oct 27. J Virol. 2020. PMID: 32847856 Free PMC article.

8

High-Throughput Screening for Drugs That Inhibit Papain-Like Protease in SARS-CoV-2.

Smith E, Davis-Gardner ME, Garcia-Ordonez RD, Nguyen TT, Hull M, Chen E, Baillargeon P, Scampavia L, Strutzenberg T, Griffin PR, Farzan M, Spicer TP. Smith E, et al. Among authors: farzan m. SLAS Discov. 2020 Dec;25(10):1152-1161. doi: 10.1177/2472555220963667. Epub 2020 Oct 10. SLAS Discov. 2020. PMID: 33043784 Free PMC article.

9

Functional importance of the D614G mutation in the SARS-CoV-2 spike protein.

Jackson CB, Zhang L, Farzan M, Choe H. Jackson CB, et al. Among authors: farzan m. Biochem Biophys Res Commun. 2021 Jan 29;538:108-115. doi: 10.1016/j.bbrc.2020.11.026. Epub 2020 Nov 13. Biochem Biophys Res Commun. 2021. PMID: 33220921 Free PMC article. Review.

10

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.

Zhang L, Jackson CB, Mou H, Ojha A, Peng H, Quinlan BD, Rangarajan ES, Pan A, Vanderheiden A, Suthar MS, Li W, Izard T, Rader C, Farzan M, Choe H. Zhang L, et al. Among authors: farzan m. Nat Commun. 2020 Nov 26;11(1):6013. doi: 10.1038/s41467-020-19808-4. Nat Commun. 2020. PMID: 33243994 Free PMC article.

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